| Reaction Details |
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 | Report a problem with these data |
| Target | N-acylethanolamine-hydrolyzing acid amidase |
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| Ligand | BDBM50151057 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1978880 (CHEMBL4612015) |
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| IC50 | 13±n/a nM |
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| Citation |  Piomelli, D; Scalvini, L; Fotio, Y; Lodola, A; Spadoni, G; Tarzia, G; Mor, M -Acylethanolamine Acid Amidase (NAAA): Structure, Function, and Inhibition. J Med Chem63:7475-7490 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| N-acylethanolamine-hydrolyzing acid amidase |
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| Name: | N-acylethanolamine-hydrolyzing acid amidase |
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| Synonyms: | ASAH-like protein | Asahl | N-acylethanolamine acid amidase (NAAA) | N-acylethanolamine-hydrolyzing acid amidase | N-acylethanolamine-hydrolyzing acid amidase (NAAA) | N-acylethanolamine-hydrolyzing acid amidase subunit alpha | N-acylethanolamine-hydrolyzing acid amidase subunit beta | N-acylsphingosine amidohydrolase-like | NAAA_RAT | Naaa |
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| Type: | Enzyme |
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| Mol. Mass.: | 40306.53 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | Q5KTC7 |
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| Residue: | 362 |
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| Sequence: | MGTPAIRAACHGAHLALALLLLLSLSDPWLWATAPGTPPLFNVSLDAAPELRWLPMLQHY
DPDFVRAAVAQVIGDRVPQWILEMIGEIVQKVESFLPQPFTSEIRGICDYLNLSLAEGVL
VNLAYEASAFCTSIVAQDSQGRIYHGRNLDYPFGNALRKLTADVQFVKNGQIVFTATTFV
GYVGLWTGQSPHKFTISGDERDKGWWWENMIAALSLGHSPISWLIRKTLTESEDFEAAVY
TLAKTPLIADVYYIVGGTSPQEGVVITRDRGGPADIWPLDPLNGAWFRVETNYDHWEPVP
KRDDRRTPAIKALNATGQAHLSLETLFQVLSVFPVYNNYTIYTTVMSAAEPDKYMTMIRN
PS
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| BDBM50151057 |
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| n/a |
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| Name | BDBM50151057 |
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| Synonyms: | CHEMBL3770726 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H24N2O3 |
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| Mol. Mass. | 268.352 |
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| SMILES | O=C(N[C@H]1CNC1=O)OCCCCC1CCCCC1 |r| |
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| Structure | 
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