| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin K |
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| Ligand | BDBM19815 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_48348 (CHEMBL663337) |
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| Ki | 70±n/a nM |
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| Citation |  Fenwick, AE; Gribble, AD; Ife, RJ; Stevens, N; Witherington, J Diastereoselective synthesis, activity and chiral stability of cyclic alkoxyketone inhibitors of cathepsin K. Bioorg Med Chem Lett11:199-202 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin K |
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| Name: | Cathepsin K |
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| Synonyms: | CATK_HUMAN | CTSK | CTSO | CTSO2 | Cathepsin O | Cathepsin O2 | Cathepsin X |
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| Type: | Enzyme |
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| Mol. Mass.: | 36975.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43235 |
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| Residue: | 329 |
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| Sequence: | MWGLKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIH
NLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVD
YRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGG
YMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVA
RVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGE
NWGNKGYILMARNKNNACGIANLASFPKM
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| BDBM19815 |
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| n/a |
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| Name | BDBM19815 |
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| Synonyms: | (2S)-2-(1-benzothiophen-2-ylformamido)-4-methyl-N-(3-oxooxan-4-yl)pentanamide | 4-amidotetrahydropyran-3-one, 39 | CHEMBL305084 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H24N2O4S |
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| Mol. Mass. | 388.481 |
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| SMILES | CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)NC1CCOCC1=O |r| |
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| Structure | 
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