| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Bromodomain-containing protein 9 |
|---|
| Ligand | BDBM50540514 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1982129 (CHEMBL4615391) |
|---|
| Ki | 251±n/a nM |
|---|
| Citation |  Clegg, MA; Bamborough, P; Chung, CW; Craggs, PD; Gordon, L; Grandi, P; Leveridge, M; Lindon, M; Liwicki, GM; Michon, AM; Molnar, J; Rioja, I; Soden, PE; Theodoulou, NH; Werner, T; Tomkinson, NCO; Prinjha, RK; Humphreys, PG Application of Atypical Acetyl-lysine Methyl Mimetics in the Development of Selective Inhibitors of the Bromodomain-Containing Protein 7 (BRD7)/Bromodomain-Containing Protein 9 (BRD9) Bromodomains. J Med Chem63:5816-5840 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Bromodomain-containing protein 9 |
|---|
| Name: | Bromodomain-containing protein 9 |
|---|
| Synonyms: | BRD9 | BRD9_HUMAN | Bromodomain-containing protein 9 | Rhabdomyosarcoma antigen MU-RMS-40.8 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 66994.30 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_108000 |
|---|
| Residue: | 597 |
|---|
| Sequence: | MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHER
ERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEP
PPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHP
MDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKQ
AALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSLTDSTAEEHVL
ALVEHAADEARDRINRFLPGGKMGYLKRNGDGSLLYSVVNTAEPDADEEETHPVDLSSLS
SKLLPGFTTLGFKDERRNKVTFLSSATTALSMQNNSVFGDLKSDEMELLYSAYGDETGVQ
CALSLQEFVKDAGSYSKKVVDDLLDQITGGDHSRTLFQLKQRRNVPMKPPDEAKVGDTLG
DSSSSVLEFMSMKSYPDVSVDISMLSSLGKVKKELDPDDSHLNLDETTKLLQDLHEAQAE
RGGSRPSSNLSSLSNASERDQHHLGSPSRLSVGEQPDVTHDPYEFLQSPEPAASAKT
|
|
|
|---|
| BDBM50540514 |
|---|
| n/a |
|---|
| Name | BDBM50540514 |
|---|
| Synonyms: | CHEMBL4636297 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H29N5O |
|---|
| Mol. Mass. | 367.4879 |
|---|
| SMILES | C\C=C/Cc1c(NCc2ccccc2N2CCN(C)CC2)cnn(C)c1=O |
|---|
| Structure | 
|
|---|
Search and Browse
