| Reaction Details |
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 | Report a problem with these data |
| Target | Bromodomain-containing protein 7 |
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| Ligand | BDBM50540522 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1982130 (CHEMBL4615392) |
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| Ki | 501±n/a nM |
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| Citation |  Clegg, MA; Bamborough, P; Chung, CW; Craggs, PD; Gordon, L; Grandi, P; Leveridge, M; Lindon, M; Liwicki, GM; Michon, AM; Molnar, J; Rioja, I; Soden, PE; Theodoulou, NH; Werner, T; Tomkinson, NCO; Prinjha, RK; Humphreys, PG Application of Atypical Acetyl-lysine Methyl Mimetics in the Development of Selective Inhibitors of the Bromodomain-Containing Protein 7 (BRD7)/Bromodomain-Containing Protein 9 (BRD9) Bromodomains. J Med Chem63:5816-5840 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Bromodomain-containing protein 7 |
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| Name: | Bromodomain-containing protein 7 |
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| Synonyms: | 75 kDa bromodomain protein | BP75 | BRD7 | BRD7_HUMAN | CELTIX1 | Protein CELTIX-1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 74135.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_107970 |
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| Residue: | 651 |
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| Sequence: | MGKKHKKHKSDKHLYEEYVEKPLKLVLKVGGNEVTELSTGSSGHDSSLFEDKNDHDKHKD
RKRKKRKKGEKQIPGEEKGRKRRRVKEDKKKRDRDRVENEAEKDLQCHAPVRLDLPPEKP
LTSSLAKQEEVEQTPLQEALNQLMRQLQRKDPSAFFSFPVTDFIAPGYSMIIKHPMDFST
MKEKIKNNDYQSIEELKDNFKLMCTNAMIYNKPETIYYKAAKKLLHSGMKILSQERIQSL
KQSIDFMADLQKTRKQKDGTDTSQSGEDGGCWQREREDSGDAEAHAFKSPSKENKKKDKD
MLEDKFKSNNLEREQEQLDRIVKESGGKLTRRLVNSQCEFERRKPDGTTTLGLLHPVDPI
VGEPGYCPVRLGMTTGRLQSGVNTLQGFKEDKRNKVTPVLYLNYGPYSSYAPHYDSTFAN
ISKDDSDLIYSTYGEDSDLPSDFSIHEFLATCQDYPYVMADSLLDVLTKGGHSRTLQEME
MSLPEDEGHTRTLDTAKEMEITEVEPPGRLDSSTQDRLIALKAVTNFGVPVEVFDSEEAE
IFQKKLDETTRLLRELQEAQNERLSTRPPPNMICLLGPSYREMHLAEQVTNNLKELAQQV
TPGDIVSTYGVRKAMGISIPSPVMENNFVDLTEDTEEPKKTDVAECGPGGS
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| BDBM50540522 |
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| n/a |
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| Name | BDBM50540522 |
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| Synonyms: | CHEMBL4639574 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H31N5O |
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| Mol. Mass. | 369.5037 |
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| SMILES | CCCCc1c(NCc2ccccc2N2CCN(C)CC2)cnn(C)c1=O |
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| Structure | 
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