| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1A |
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| Ligand | BDBM50094674 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_897 |
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| Ki | 0.230000±n/a nM |
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| Citation |  Laban, U; Kurrasch-Orbaugh, D; Marona-Lewicka, D; Nichols, DE A novel fluorinated tryptamine with highly potent serotonin 5-HT1A receptor agonist properties. Bioorg Med Chem Lett11:793-5 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1A |
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| Name: | 5-hydroxytryptamine receptor 1A |
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| Synonyms: | 5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A |
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| Type: | n/a |
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| Mol. Mass.: | 46122.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 422 |
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| Sequence: | MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
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|
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| BDBM50094674 |
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| n/a |
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| Name | BDBM50094674 |
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| Synonyms: | CHEMBL142862 | [2-(4-Fluoro-5-methoxy-1H-indol-3-yl)-ethyl]-dimethyl-amine |
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| Type | Small organic molecule |
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| Emp. Form. | C13H17FN2O |
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| Mol. Mass. | 236.2853 |
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| SMILES | COc1ccc2[nH]cc(CCN(C)C)c2c1F |
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| Structure | 
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