Compile Data Set for Download or QSAR

Found 346 hits with Last Name = 'marona-lewicka' and Initial = 'd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50068612 (2-(8-Bromo-benzo[1,2-b;4,5-b']difuran-4-yl)-1-meth...) Show SMILES CC(N)Cc1c2ccoc2c(Br)c2ccoc12 Show InChI InChI=1S/C13H12BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h2-5,7H,6,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding activity against cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI as the radioligand.				J Med Chem 41: 5148-9 (1999) Article DOI: 10.1021/jm9803525 BindingDB Entry DOI: 10.7270/Q2862FKX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50068612 (2-(8-Bromo-benzo[1,2-b;4,5-b']difuran-4-yl)-1-meth...) Show SMILES CC(N)Cc1c2ccoc2c(Br)c2ccoc12 Show InChI InChI=1S/C13H12BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h2-5,7H,6,15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding activity against cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI as the radioligand.				J Med Chem 41: 5148-9 (1999) Article DOI: 10.1021/jm9803525 BindingDB Entry DOI: 10.7270/Q2862FKX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50094670 (1-(4-Dipropylamino-1,3,4,5-tetrahydro-benzo[cd]ind...) Show SMILES CCCN(CCC)C1Cc2c[nH]c3ccc(C(C)=O)c(C1)c23 Show InChI InChI=1S/C19H26N2O/c1-4-8-21(9-5-2)15-10-14-12-20-18-7-6-16(13(3)22)17(11-15)19(14)18/h6-7,12,15,20H,4-5,8-11H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.0880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition constant of 50 microM forskolin-stimulated cAMP accumulation against 5-hydroxytryptamine 1A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50097891 (4-Fluoro-5-methoxy-3-(2-pyrrolidin-1-yl-ethyl)-1H-...) Show SMILES COc1ccc2[nH]cc(CCN3CCCC3)c2c1F Show InChI InChI=1S/C15H19FN2O/c1-19-13-5-4-12-14(15(13)16)11(10-17-12)6-9-18-7-2-3-8-18/h4-5,10,17H,2-3,6-9H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinitty towards human 5-hydroxytryptamine 1A receptor was determined using [3H]-8-OH-DPAT-as radioligand				Bioorg Med Chem Lett 11: 793-5 (2001) BindingDB Entry DOI: 10.7270/Q2ZC824R
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50068612 (2-(8-Bromo-benzo[1,2-b;4,5-b']difuran-4-yl)-1-meth...) Show SMILES CC(N)Cc1c2ccoc2c(Br)c2ccoc12 Show InChI InChI=1S/C13H12BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h2-5,7H,6,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding activity against cloned human 5-hydroxytryptamine 2B receptor using [3H]-5-HT as the radioligand.				J Med Chem 41: 5148-9 (1999) Article DOI: 10.1021/jm9803525 BindingDB Entry DOI: 10.7270/Q2862FKX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50068612 (2-(8-Bromo-benzo[1,2-b;4,5-b']difuran-4-yl)-1-meth...) Show SMILES CC(N)Cc1c2ccoc2c(Br)c2ccoc12 Show InChI InChI=1S/C13H12BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h2-5,7H,6,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Antagonistic activity measured for 5-hydroxytryptamine 2A receptor using [3H]-MDL- 100,907 as radioligand in rat cortical homogenates.				J Med Chem 41: 5148-9 (1999) Article DOI: 10.1021/jm9803525 BindingDB Entry DOI: 10.7270/Q2862FKX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50094674 (CHEMBL142862 | [2-(4-Fluoro-5-methoxy-1H-indol-3-y...) Show SMILES COc1ccc2[nH]cc(CCN(C)C)c2c1F Show InChI InChI=1S/C13H17FN2O/c1-16(2)7-6-9-8-15-10-4-5-11(17-3)13(14)12(9)10/h4-5,8,15H,6-7H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinitty towards human 5-hydroxytryptamine 1A receptor was determined using [3H]-8-OH-DPAT-as radioligand				Bioorg Med Chem Lett 11: 793-5 (2001) BindingDB Entry DOI: 10.7270/Q2ZC824R
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50194747 (((R)-4-bromo-3,6-dimethoxybenzocyclobuten-1-yl)met...) Show SMILES COc1cc(Br)c(OC)c2C[C@@H](CN)c12 Show InChI InChI=1S/C11H14BrNO2/c1-14-9-4-8(12)11(15-2)7-3-6(5-13)10(7)9/h4,6H,3,5,13H2,1-2H3/t6-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of (+/-)-[125I]DOI from rat cloned 5HT2A receptor				J Med Chem 49: 5794-803 (2006) Article DOI: 10.1021/jm060656o BindingDB Entry DOI: 10.7270/Q2NS0TH3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50052337 (2-(8-bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...) Show SMILES CC(N)Cc1c2CCOc2c(Br)c2CCOc12 Show InChI InChI=1S/C13H16BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h7H,2-6,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonistic activity at cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI as radioligand				J Med Chem 39: 2953-61 (1996) Article DOI: 10.1021/jm960199j BindingDB Entry DOI: 10.7270/Q28914ZS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50064703 ((R)-2-(8-Bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-...) Show SMILES C[C@@H](N)Cc1c2CCOc2c(Br)c2CCOc12 Show InChI InChI=1S/C13H16BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h7H,2-6,15H2,1H3/t7-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding ability of compound at cloned human 5-hydroxytryptamine 2C receptor using [125 I]DOI as radioligand				J Med Chem 41: 2134-45 (1998) Article DOI: 10.1021/jm980076u BindingDB Entry DOI: 10.7270/Q2XD10T8
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50052337 (2-(8-bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...) Show SMILES CC(N)Cc1c2CCOc2c(Br)c2CCOc12 Show InChI InChI=1S/C13H16BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h7H,2-6,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding activity against cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI as the radioligand.				J Med Chem 41: 5148-9 (1999) Article DOI: 10.1021/jm9803525 BindingDB Entry DOI: 10.7270/Q2862FKX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50033872 ((6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,...) Show SMILES CCCC[C@@H](C)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:24| Show InChI InChI=1S/C22H29N3O/c1-4-5-7-14(2)24-22(26)16-10-18-17-8-6-9-19-21(17)15(12-23-19)11-20(18)25(3)13-16/h6,8-10,12,14,16,20,23H,4-5,7,11,13H2,1-3H3,(H,24,26)/t14-,16-,20-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was measured against 5-hydroxytryptamine 1A receptor by displacement of [3H]-8-OH-DPAT by lysergic acid amides				J Med Chem 38: 958-66 (1995) BindingDB Entry DOI: 10.7270/Q2NZ86N6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50194747 (((R)-4-bromo-3,6-dimethoxybenzocyclobuten-1-yl)met...) Show SMILES COc1cc(Br)c(OC)c2C[C@@H](CN)c12 Show InChI InChI=1S/C11H14BrNO2/c1-14-9-4-8(12)11(15-2)7-3-6(5-13)10(7)9/h4,6H,3,5,13H2,1-2H3/t6-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of (+/-)-[125I]DOI from human cloned 5HT2A receptor				J Med Chem 49: 5794-803 (2006) Article DOI: 10.1021/jm060656o BindingDB Entry DOI: 10.7270/Q2NS0TH3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50118579 ((2,4-Dimethyl-azetidin-1-yl)-(7-methyl-4,6,6a,7,8,...) Show SMILES C[C@H]1C[C@H](C)N1C(=O)[C@H]1CN(C)C2Cc3c[nH]c4cccc(C2=C1)c34 |c:24| Show InChI InChI=1S/C21H25N3O/c1-12-7-13(2)24(12)21(25)15-8-17-16-5-4-6-18-20(16)14(10-22-18)9-19(17)23(3)11-15/h4-6,8,10,12-13,15,19,22H,7,9,11H2,1-3H3/t12-,13-,15+,19?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligand				J Med Chem 45: 4344-9 (2002) BindingDB Entry DOI: 10.7270/Q2765G2F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM28582 (1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine | CHE...) Show SMILES COc1cc(CC(C)N)c(OC)cc1I Show InChI InChI=1S/C11H16INO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding activity against cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI as the radioligand.				J Med Chem 41: 5148-9 (1999) Article DOI: 10.1021/jm9803525 BindingDB Entry DOI: 10.7270/Q2862FKX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50052337 (2-(8-bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...) Show SMILES CC(N)Cc1c2CCOc2c(Br)c2CCOc12 Show InChI InChI=1S/C13H16BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h7H,2-6,15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonistic activity at cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI as radioligand				J Med Chem 39: 2953-61 (1996) Article DOI: 10.1021/jm960199j BindingDB Entry DOI: 10.7270/Q28914ZS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50064703 ((R)-2-(8-Bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-...) Show SMILES C[C@@H](N)Cc1c2CCOc2c(Br)c2CCOc12 Show InChI InChI=1S/C13H16BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h7H,2-6,15H2,1H3/t7-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding ability of compound at cloned human 5-hydroxytryptamine 2A receptor using [125 I]DOI as radioligand				J Med Chem 41: 2134-45 (1998) Article DOI: 10.1021/jm980076u BindingDB Entry DOI: 10.7270/Q2XD10T8
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50052337 (2-(8-bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...) Show SMILES CC(N)Cc1c2CCOc2c(Br)c2CCOc12 Show InChI InChI=1S/C13H16BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h7H,2-6,15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding activity against cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI as the radioligand.				J Med Chem 41: 5148-9 (1999) Article DOI: 10.1021/jm9803525 BindingDB Entry DOI: 10.7270/Q2862FKX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50033869 ((6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,...) Show SMILES CCC[C@@H](C)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:23| Show InChI InChI=1S/C21H27N3O/c1-4-6-13(2)23-21(25)15-9-17-16-7-5-8-18-20(16)14(11-22-18)10-19(17)24(3)12-15/h5,7-9,11,13,15,19,22H,4,6,10,12H2,1-3H3,(H,23,25)/t13-,15-,19-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was measured against 5-hydroxytryptamine 1A receptor by displacement of [3H]-8-OH-DPAT by lysergic acid amides				J Med Chem 38: 958-66 (1995) BindingDB Entry DOI: 10.7270/Q2NZ86N6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50005267 (2,5-dimethoxy-4-bromophenethylamine | 2-(4-Bromo-2...) Show SMILES COc1cc(CCN)c(OC)cc1Br Show InChI InChI=1S/C10H14BrNO2/c1-13-9-6-8(11)10(14-2)5-7(9)3-4-12/h5-6H,3-4,12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	0.660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of (+/-)-[125I]DOI from human cloned 5HT2A receptor				J Med Chem 49: 5794-803 (2006) Article DOI: 10.1021/jm060656o BindingDB Entry DOI: 10.7270/Q2NS0TH3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50194752 ((+/-)-(4-bromo-3,6-dimethoxybenzocyclobuten-1-yl)m...) Show SMILES COc1cc(Br)c(OC)c2CC(CN)c12 Show InChI InChI=1S/C11H14BrNO2/c1-14-9-4-8(12)11(15-2)7-3-6(5-13)10(7)9/h4,6H,3,5,13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.730	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of (+/-)-[125I]DOI from human cloned 5HT2A receptor				J Med Chem 49: 5794-803 (2006) Article DOI: 10.1021/jm060656o BindingDB Entry DOI: 10.7270/Q2NS0TH3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50194752 ((+/-)-(4-bromo-3,6-dimethoxybenzocyclobuten-1-yl)m...) Show SMILES COc1cc(Br)c(OC)c2CC(CN)c12 Show InChI InChI=1S/C11H14BrNO2/c1-14-9-4-8(12)11(15-2)7-3-6(5-13)10(7)9/h4,6H,3,5,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of (+/-)-[125I]DOI from rat cloned 5HT2A receptor				J Med Chem 49: 5794-803 (2006) Article DOI: 10.1021/jm060656o BindingDB Entry DOI: 10.7270/Q2NS0TH3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50052339 (2-(8-Bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...) Show SMILES NCCc1c2CCOc2c(Br)c2CCOc12 Show InChI InChI=1S/C12H14BrNO2/c13-10-9-3-6-15-11(9)7(1-4-14)8-2-5-16-12(8)10/h1-6,14H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity of the compound towards rat hippocampal 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand				J Med Chem 39: 2953-61 (1996) Article DOI: 10.1021/jm960199j BindingDB Entry DOI: 10.7270/Q28914ZS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM21393 (7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...) Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1 Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.830	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinitty towards human 5-hydroxytryptamine 1A receptor was determined using [3H]-8-OH-DPAT-as radioligand				Bioorg Med Chem Lett 11: 793-5 (2001) BindingDB Entry DOI: 10.7270/Q2ZC824R
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50005267 (2,5-dimethoxy-4-bromophenethylamine | 2-(4-Bromo-2...) Show SMILES COc1cc(CCN)c(OC)cc1Br Show InChI InChI=1S/C10H14BrNO2/c1-13-9-6-8(11)10(14-2)5-7(9)3-4-12/h5-6H,3-4,12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	0.880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of (+/-)-[125I]DOI from rat cloned 5HT2A receptor				J Med Chem 49: 5794-803 (2006) Article DOI: 10.1021/jm060656o BindingDB Entry DOI: 10.7270/Q2NS0TH3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50052337 (2-(8-bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...) Show SMILES CC(N)Cc1c2CCOc2c(Br)c2CCOc12 Show InChI InChI=1S/C13H16BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h7H,2-6,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-La Crosse Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from rat 5HT2A receptor expressed in mouse NIH3T3 cells				Bioorg Med Chem 16: 6242-51 (2008) Article DOI: 10.1016/j.bmc.2008.04.030 BindingDB Entry DOI: 10.7270/Q2QZ29R4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50271489 (1-(4-Bromo-7,8-dihydro-6H-furo[2,3-g]chromen-9-yl)...) Show SMILES CC(N)Cc1c2CCCOc2c(Br)c2ccoc12 Show InChI InChI=1S/C14H16BrNO2/c1-8(16)7-11-9-3-2-5-17-14(9)12(15)10-4-6-18-13(10)11/h4,6,8H,2-3,5,7,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-La Crosse Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from rat 5HT2A receptor expressed in mouse NIH3T3 cells				Bioorg Med Chem 16: 6242-51 (2008) Article DOI: 10.1016/j.bmc.2008.04.030 BindingDB Entry DOI: 10.7270/Q2QZ29R4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50118576 ((2,4-Dimethyl-azetidin-1-yl)-(7-methyl-4,6,6a,7,8,...) Show SMILES C[C@H]1C[C@@H](C)N1C(=O)[C@H]1CN(C)C2Cc3c[nH]c4cccc(C2=C1)c34 |c:24| Show InChI InChI=1S/C21H25N3O/c1-12-7-13(2)24(12)21(25)15-8-17-16-5-4-6-18-20(16)14(10-22-18)9-19(17)23(3)11-15/h4-6,8,10,12-13,15,19,22H,7,9,11H2,1-3H3/t12-,13+,15-,19?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligand				J Med Chem 45: 4344-9 (2002) BindingDB Entry DOI: 10.7270/Q2765G2F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM21342 ((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...) Show SMILES [H][C@@]12Cc3c[nH]c4cccc(C1=C[C@H](CN2C)C(=O)N(CC)CC)c34 |c:12| Show InChI InChI=1S/C20H25N3O/c1-4-23(5-2)20(24)14-9-16-15-7-6-8-17-19(15)13(11-21-17)10-18(16)22(3)12-14/h6-9,11,14,18,21H,4-5,10,12H2,1-3H3/t14-,18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligand				J Med Chem 45: 4344-9 (2002) BindingDB Entry DOI: 10.7270/Q2765G2F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50131665 (C-(8-Bromo-6-methoxy-4,5-dihydro-3H-naphtho[1,8-bc...) Show SMILES COc1cc(Br)c2occ3CC[C@@H](CN)c1c23 Show InChI InChI=1S/C13H14BrNO2/c1-16-10-4-9(14)13-12-8(6-17-13)3-2-7(5-15)11(10)12/h4,6-7H,2-3,5,15H2,1H3/t7-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description In vitro binding to 5-hydroxytryptamine 2C receptor using [125 I]-DOI				J Med Chem 46: 3526-35 (2003) Article DOI: 10.1021/jm030064v BindingDB Entry DOI: 10.7270/Q20P0ZC1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM21342 ((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...) Show SMILES [H][C@@]12Cc3c[nH]c4cccc(C1=C[C@H](CN2C)C(=O)N(CC)CC)c34 |c:12| Show InChI InChI=1S/C20H25N3O/c1-4-23(5-2)20(24)14-9-16-15-7-6-8-17-19(15)13(11-21-17)10-18(16)22(3)12-14/h6-9,11,14,18,21H,4-5,10,12H2,1-3H3/t14-,18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Tested in vitro for its ability to bind to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand				J Med Chem 46: 3526-35 (2003) Article DOI: 10.1021/jm030064v BindingDB Entry DOI: 10.7270/Q20P0ZC1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50052337 (2-(8-bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...) Show SMILES CC(N)Cc1c2CCOc2c(Br)c2CCOc12 Show InChI InChI=1S/C13H16BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h7H,2-6,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Antagonistic activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]-rauwolscine as radioligand				J Med Chem 39: 2953-61 (1996) Article DOI: 10.1021/jm960199j BindingDB Entry DOI: 10.7270/Q28914ZS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50064703 ((R)-2-(8-Bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-...) Show SMILES C[C@@H](N)Cc1c2CCOc2c(Br)c2CCOc12 Show InChI InChI=1S/C13H16BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h7H,2-6,15H2,1H3/t7-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding ability of compound at cloned human 5-hydroxytryptamine 2B receptor using [3H]-rauwolscine as radioligand				J Med Chem 41: 2134-45 (1998) Article DOI: 10.1021/jm980076u BindingDB Entry DOI: 10.7270/Q2XD10T8
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50052337 (2-(8-bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...) Show SMILES CC(N)Cc1c2CCOc2c(Br)c2CCOc12 Show InChI InChI=1S/C13H16BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h7H,2-6,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding activity against cloned human 5-hydroxytryptamine 2B receptor using [3H]-5-HT as the radioligand.				J Med Chem 41: 5148-9 (1999) Article DOI: 10.1021/jm9803525 BindingDB Entry DOI: 10.7270/Q2862FKX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50052337 (2-(8-bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...) Show SMILES CC(N)Cc1c2CCOc2c(Br)c2CCOc12 Show InChI InChI=1S/C13H16BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h7H,2-6,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonistic activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]-5-HT as radioligand				J Med Chem 39: 2953-61 (1996) Article DOI: 10.1021/jm960199j BindingDB Entry DOI: 10.7270/Q28914ZS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50064703 ((R)-2-(8-Bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-...) Show SMILES C[C@@H](N)Cc1c2CCOc2c(Br)c2CCOc12 Show InChI InChI=1S/C13H16BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h7H,2-6,15H2,1H3/t7-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding ability of compound at cloned human 5-hydroxytryptamine 2B receptor using [3H]-5-HT 2B as radioligand				J Med Chem 41: 2134-45 (1998) Article DOI: 10.1021/jm980076u BindingDB Entry DOI: 10.7270/Q2XD10T8
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50094673 (CHEMBL342986 | Diethyl-[2-(5-methoxy-1H-indol-3-yl...) Show SMILES CCN(CC)CCc1c[nH]c2ccc(OC)cc12 Show InChI InChI=1S/C15H22N2O/c1-4-17(5-2)9-8-12-11-16-15-7-6-13(18-3)10-14(12)15/h6-7,10-11,16H,4-5,8-9H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Evaluated for the binding constant at [3H]-8-OH-DPAT-labeled human 5-hydroxytryptamine 1A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM28582 (1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine | CHE...) Show SMILES COc1cc(CC(C)N)c(OC)cc1I Show InChI InChI=1S/C11H16INO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding activity against cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI as the radioligand.				J Med Chem 41: 5148-9 (1999) Article DOI: 10.1021/jm9803525 BindingDB Entry DOI: 10.7270/Q2862FKX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50118577 ((2,4-Dimethyl-azetidin-1-yl)-(7-methyl-4,6,6a,7,8,...) Show SMILES C[C@@H]1C[C@@H](C)N1C(=O)[C@H]1CN(C)C2Cc3c[nH]c4cccc(C2=C1)c34 |c:24| Show InChI InChI=1S/C21H25N3O/c1-12-7-13(2)24(12)21(25)15-8-17-16-5-4-6-18-20(16)14(10-22-18)9-19(17)23(3)11-15/h4-6,8,10,12-13,15,19,22H,7,9,11H2,1-3H3/t12-,13-,15-,19?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinities against 5-hydroxytryptamine 1D receptor alpha				J Med Chem 45: 4344-9 (2002) BindingDB Entry DOI: 10.7270/Q2765G2F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50008224 ((6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,...) Show SMILES CC[C@@H](C)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:22| Show InChI InChI=1S/C20H25N3O/c1-4-12(2)22-20(24)14-8-16-15-6-5-7-17-19(15)13(10-21-17)9-18(16)23(3)11-14/h5-8,10,12,14,18,21H,4,9,11H2,1-3H3,(H,22,24)/t12-,14-,18-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was measured against 5-hydroxytryptamine 1A receptor by displacement of [3H]-8-OH-DPAT by lysergic acid amides				J Med Chem 38: 958-66 (1995) BindingDB Entry DOI: 10.7270/Q2NZ86N6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50033874 ((6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,...) Show SMILES CCC(CC)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:23| Show InChI InChI=1S/C21H27N3O/c1-4-15(5-2)23-21(25)14-9-17-16-7-6-8-18-20(16)13(11-22-18)10-19(17)24(3)12-14/h6-9,11,14-15,19,22H,4-5,10,12H2,1-3H3,(H,23,25)/t14-,19-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was measured against 5-hydroxytryptamine 1A receptor by displacement of [3H]-8-OH-DPAT by lysergic acid amides				J Med Chem 38: 958-66 (1995) BindingDB Entry DOI: 10.7270/Q2NZ86N6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50005257 ((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...) Show SMILES COc1cc(CC(C)N)c(OC)cc1Br Show InChI InChI=1S/C11H16BrNO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description In vitro binding to 5-hydroxytryptamine 2A receptor using [125 I]-DOI				J Med Chem 46: 3526-35 (2003) Article DOI: 10.1021/jm030064v BindingDB Entry DOI: 10.7270/Q20P0ZC1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50052337 (2-(8-bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...) Show SMILES CC(N)Cc1c2CCOc2c(Br)c2CCOc12 Show InChI InChI=1S/C13H16BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h7H,2-6,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Antagonistic activity at cloned human 5-hydroxytryptamine 2C receptor using [3H]-mesulergine as radioligand				J Med Chem 39: 2953-61 (1996) Article DOI: 10.1021/jm960199j BindingDB Entry DOI: 10.7270/Q28914ZS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50064703 ((R)-2-(8-Bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-...) Show SMILES C[C@@H](N)Cc1c2CCOc2c(Br)c2CCOc12 Show InChI InChI=1S/C13H16BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h7H,2-6,15H2,1H3/t7-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding ability of compound at cloned human 5-hydroxytryptamine 2C receptor using [3H]- mesulergine as radioligand				J Med Chem 41: 2134-45 (1998) Article DOI: 10.1021/jm980076u BindingDB Entry DOI: 10.7270/Q2XD10T8
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50118579 ((2,4-Dimethyl-azetidin-1-yl)-(7-methyl-4,6,6a,7,8,...) Show SMILES C[C@H]1C[C@H](C)N1C(=O)[C@H]1CN(C)C2Cc3c[nH]c4cccc(C2=C1)c34 |c:24| Show InChI InChI=1S/C21H25N3O/c1-12-7-13(2)24(12)21(25)15-8-17-16-5-4-6-18-20(16)14(10-22-18)9-19(17)23(3)11-15/h4-6,8,10,12-13,15,19,22H,7,9,11H2,1-3H3/t12-,13-,15+,19?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinities towards 5-hydroxytryptamine 1D receptor alpha				J Med Chem 45: 4344-9 (2002) BindingDB Entry DOI: 10.7270/Q2765G2F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50131665 (C-(8-Bromo-6-methoxy-4,5-dihydro-3H-naphtho[1,8-bc...) Show SMILES COc1cc(Br)c2occ3CC[C@@H](CN)c1c23 Show InChI InChI=1S/C13H14BrNO2/c1-16-10-4-9(14)13-12-8(6-17-13)3-2-7(5-15)11(10)12/h4,6-7H,2-3,5,15H2,1H3/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description In vitro binding to 5-hydroxytryptamine 2A receptor using [125 I]-DOI				J Med Chem 46: 3526-35 (2003) Article DOI: 10.1021/jm030064v BindingDB Entry DOI: 10.7270/Q20P0ZC1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50131668 (C-(8-Bromo-6-methoxy-2a,3,4,5-tetrahydro-2H-naphth...) Show SMILES COc1cc(Br)c2OC[C@H]3CC[C@@H](CN)c1c23 Show InChI InChI=1S/C13H16BrNO2/c1-16-10-4-9(14)13-12-8(6-17-13)3-2-7(5-15)11(10)12/h4,7-8H,2-3,5-6,15H2,1H3/t7-,8+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description In vitro binding to 5-hydroxytryptamine 2C receptor using [125 I]-DOI				J Med Chem 46: 3526-35 (2003) Article DOI: 10.1021/jm030064v BindingDB Entry DOI: 10.7270/Q20P0ZC1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50005257 ((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...) Show SMILES COc1cc(CC(C)N)c(OC)cc1Br Show InChI InChI=1S/C11H16BrNO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description In vitro binding to 5-hydroxytryptamine 2C receptor using [125 I]-DOI				J Med Chem 46: 3526-35 (2003) Article DOI: 10.1021/jm030064v BindingDB Entry DOI: 10.7270/Q20P0ZC1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50271484 (2-(10-Bromo-2,3,4,7,8,9-hexahydro-pyrano[2,3-g]chr...) Show SMILES CC(N)Cc1c2CCCOc2c(Br)c2CCCOc12 Show InChI InChI=1S/C15H20BrNO2/c1-9(17)8-12-10-4-2-7-19-15(10)13(16)11-5-3-6-18-14(11)12/h9H,2-8,17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-La Crosse Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from rat 5HT2A receptor expressed in mouse NIH3T3 cells				Bioorg Med Chem 16: 6242-51 (2008) Article DOI: 10.1016/j.bmc.2008.04.030 BindingDB Entry DOI: 10.7270/Q2QZ29R4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50033873 ((6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,...) Show SMILES CCCCC[C@@H](C)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:25| Show InChI InChI=1S/C23H31N3O/c1-4-5-6-8-15(2)25-23(27)17-11-19-18-9-7-10-20-22(18)16(13-24-20)12-21(19)26(3)14-17/h7,9-11,13,15,17,21,24H,4-6,8,12,14H2,1-3H3,(H,25,27)/t15-,17-,21-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was measured against 5-hydroxytryptamine 1A receptor by displacement of [3H]-8-OH-DPAT by lysergic acid amides				J Med Chem 38: 958-66 (1995) BindingDB Entry DOI: 10.7270/Q2NZ86N6
					More data for this Ligand-Target Pair

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