BindingDB PrimarySearch

BDBM50094670 1-(4-Dipropylamino-1,3,4,5-tetrahydro-benzo[cd]indol-6-yl)-ethanone::CHEMBL276031::LY 293284::LY-293284::LY-293384

SMILES: CCCN(CCC)C1Cc2c[nH]c3ccc(C(C)=O)c(C1)c23

InChI Key: InChIKey=CKYZLYQSDNLGPT-UHFFFAOYSA-N

Data: 15 KI 1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50094670
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50094670 (1-(4-Dipropylamino-1,3,4,5-tetrahydro-benzo[cd]ind...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.0880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition constant of 50 microM forskolin-stimulated cAMP accumulation against 5-hydroxytryptamine 1A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
HTR1D (RAT)	BDBM50094670 (1-(4-Dipropylamino-1,3,4,5-tetrahydro-benzo[cd]ind...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	66.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by PDSP K_i Database									J Pharmacol Exp Ther 270: 1270-81 (1994) BindingDB Entry DOI: 10.7270/Q2805146
Eli Lilly and Company Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50094670 (1-(4-Dipropylamino-1,3,4,5-tetrahydro-benzo[cd]ind...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by PDSP K_i Database									J Pharmacol Exp Ther 270: 1270-81 (1994) BindingDB Entry DOI: 10.7270/Q2805146
Eli Lilly and Company Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50094670 (1-(4-Dipropylamino-1,3,4,5-tetrahydro-benzo[cd]ind...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by PDSP K_i Database									J Pharmacol Exp Ther 270: 1270-81 (1994) BindingDB Entry DOI: 10.7270/Q2805146
Eli Lilly and Company Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (RAT)	BDBM50094670 (1-(4-Dipropylamino-1,3,4,5-tetrahydro-benzo[cd]ind...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by PDSP K_i Database									J Pharmacol Exp Ther 270: 1270-81 (1994) BindingDB Entry DOI: 10.7270/Q2805146
Eli Lilly and Company Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50094670 (1-(4-Dipropylamino-1,3,4,5-tetrahydro-benzo[cd]ind...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by PDSP K_i Database									J Pharmacol Exp Ther 270: 1270-81 (1994) BindingDB Entry DOI: 10.7270/Q2805146
Eli Lilly and Company Curated by PDSP K_i Database					More data for this Ligand-Target Pair
adrenergic Alpha2 (RAT)	BDBM50094670 (1-(4-Dipropylamino-1,3,4,5-tetrahydro-benzo[cd]ind...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by PDSP K_i Database									J Pharmacol Exp Ther 270: 1270-81 (1994) BindingDB Entry DOI: 10.7270/Q2805146
Eli Lilly and Company Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Rattus norvegicus)	BDBM50094670 (1-(4-Dipropylamino-1,3,4,5-tetrahydro-benzo[cd]ind...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by PDSP K_i Database									J Pharmacol Exp Ther 270: 1270-81 (1994) BindingDB Entry DOI: 10.7270/Q2805146
Eli Lilly and Company Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50094670 (1-(4-Dipropylamino-1,3,4,5-tetrahydro-benzo[cd]ind...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by PDSP K_i Database									J Pharmacol Exp Ther 270: 1270-81 (1994) BindingDB Entry DOI: 10.7270/Q2805146
Eli Lilly and Company Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50094670 (1-(4-Dipropylamino-1,3,4,5-tetrahydro-benzo[cd]ind...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by PDSP K_i Database									J Pharmacol Exp Ther 270: 1270-81 (1994) BindingDB Entry DOI: 10.7270/Q2805146
Eli Lilly and Company Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50094670 (1-(4-Dipropylamino-1,3,4,5-tetrahydro-benzo[cd]ind...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by PDSP K_i Database									J Pharmacol Exp Ther 270: 1270-81 (1994) BindingDB Entry DOI: 10.7270/Q2805146
Eli Lilly and Company Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Rattus norvegicus (Rat))	BDBM50094670 (1-(4-Dipropylamino-1,3,4,5-tetrahydro-benzo[cd]ind...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by PDSP K_i Database									J Pharmacol Exp Ther 270: 1270-81 (1994) BindingDB Entry DOI: 10.7270/Q2805146
Eli Lilly and Company Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Rattus norvegicus (Rat))	BDBM50094670 (1-(4-Dipropylamino-1,3,4,5-tetrahydro-benzo[cd]ind...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by PDSP K_i Database									J Pharmacol Exp Ther 270: 1270-81 (1994) BindingDB Entry DOI: 10.7270/Q2805146
Eli Lilly and Company Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Histamine H1 receptor (RAT)	BDBM50094670 (1-(4-Dipropylamino-1,3,4,5-tetrahydro-benzo[cd]ind...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by PDSP K_i Database									J Pharmacol Exp Ther 270: 1270-81 (1994) BindingDB Entry DOI: 10.7270/Q2805146
Eli Lilly and Company Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Serotonin 1B/1D receptor (Rattus norvegicus (Rat))	BDBM50094670 (1-(4-Dipropylamino-1,3,4,5-tetrahydro-benzo[cd]ind...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by PDSP K_i Database									J Pharmacol Exp Ther 270: 1270-81 (1994) BindingDB Entry DOI: 10.7270/Q2805146
Eli Lilly and Company Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50094670 (1-(4-Dipropylamino-1,3,4,5-tetrahydro-benzo[cd]ind...) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	0.130	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description EC50 for inhibition of 50 microM forskolin-stimulated cAMP accumulation against 5-hydroxytryptamine 1A receptor				J Med Chem 43: 4701-10 (2001) BindingDB Entry DOI: 10.7270/Q2HT2NM7
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair