| Reaction Details |
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 | Report a problem with these data |
| Target | Tubulin alpha-1A chain |
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| Ligand | BDBM50098052 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_211865 |
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| IC50 | 1400±n/a nM |
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| Citation |  Gwaltney, SL; Imade, HM; Barr, KJ; Li, Q; Gehrke, L; Credo, RB; Warner, RB; Lee, JY; Kovar, P; Wang, J; Nukkala, MA; Zielinski, NA; Frost, D; Ng, SC; Sham, HL Novel sulfonate analogues of combretastatin A-4: potent antimitotic agents. Bioorg Med Chem Lett11:871-4 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Tubulin alpha-1A chain |
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| Name: | Tubulin alpha-1A chain |
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| Synonyms: | TBA1A_PIG | TUBA1A | Tubulin | Tubulin alpha chain | Tubulin alpha-1A chain |
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| Type: | Protein |
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| Mol. Mass.: | 50049.25 |
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| Organism: | Sus scrofa (Pig) |
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| Description: | P02550 |
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| Residue: | 451 |
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| Sequence: | MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD
RIRKLADQCTGLQGFSVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA
VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA
SLRFDGALNVDLTEFQTNLVPYPRAHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYEPP
TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
AREDMAALEKDYEEVGVDSVEGEGEEEGEEY
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| BDBM50098052 |
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| n/a |
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| Name | BDBM50098052 |
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| Synonyms: | 3,4,5-Trimethoxy-benzenesulfonic acid 1-methyl-1H-indol-5-yl ester | CHEMBL169298 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H19NO6S |
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| Mol. Mass. | 377.412 |
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| SMILES | COc1cc(cc(OC)c1OC)S(=O)(=O)Oc1ccc2n(C)ccc2c1 |
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| Structure | 
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