Ki Summary

Reaction Details

Report a problem with these data

Target

C-C chemokine receptor type 1

Ligand

BDBM50098641

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_218695 (CHEMBL821481)

IC50

63±n/a nM

Citation

Naya, A; Sagara, Y; Ohwaki, K; Saeki, T; Ichikawa, D; Iwasawa, Y; Noguchi, K; Ohtake, N Design, synthesis, and discovery of a novel CCR1 antagonist. J Med Chem44:1429-35 (2001) [PubMed]

More Info.:

Get all data from this article, Assay Method

C-C chemokine receptor type 1

Name:

C-C chemokine receptor type 1

Synonyms:

Type:

PROTEIN

Mol. Mass.:

40904.59

Organism:

Mus musculus

Description:

ChEMBL_1452291

Residue:

355

Sequence:

MEISDFTEAYPTTTEFDYGDSTPCQKTAVRAFGAGLLPPLYSLVFIIGVVGNVLVILVLM
QHRRLQSMTSIYLFNLAVSDLVFLFTLPFWIDYKLKDDWIFGDAMCKLLSGFYYLGLYSE
IFFIILLTIDRYLAIVHAVFALRARTVTFGIITSIITWALAILASMPALYFFKAQWEFTH
RTCSPHFPYKSLKQWKRFQALKLNLLGLILPLLVMIICYAGIIRILLRRPSEKKVKAVRL
IFAITLLFFLLWTPYNLSVFVSAFQDVLFTNQCEQSKQLDLAMQVTEVIAYTHCCVNPII
YVFVGERFWKYLRQLFQRHVAIPLAKWLPFLSVDQLERTSSISPSTGEHELSAGF

BDBM50098641

n/a

Name

BDBM50098641

Synonyms:

1-Cyclooct-1-enylmethyl-1-ethyl-4-[(9H-xanthene-9-carbonyl)-amino]-piperidinium; iodide | CHEMBL34732

Type

Small organic molecule

Emp. Form.

C30H39N2O2

Mol. Mass.

459.6423

SMILES

CC[N+]1(C\C2=C\CCCCCC2)CCC(CC1)NC(=O)C1c2ccccc2Oc2ccccc12 |t:4,(7.65,-27.47,;6.33,-28.27,;6.35,-29.81,;7.68,-30.58,;9.25,-29.88,;10.66,-30.48,;12.1,-29.88,;12.68,-28.47,;12.1,-27.02,;10.66,-26.45,;9.25,-27.05,;8.66,-28.47,;5,-29.05,;3.67,-29.81,;3.57,-31.55,;5.04,-32.12,;6.38,-31.32,;2.22,-32.32,;1.03,-31.32,;1.01,-29.81,;-.31,-32.12,;-.31,-33.66,;1.01,-34.44,;1.01,-35.97,;-.34,-36.71,;-1.66,-35.94,;-1.66,-34.43,;-3,-33.66,;-2.97,-32.12,;-4.29,-31.36,;-4.32,-29.81,;-2.97,-29.04,;-1.63,-29.81,;-1.63,-31.32,)|

Structure