Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | C-C chemokine receptor type 1 | ||
| Ligand | BDBM50098636 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_218695 (CHEMBL821481) | ||
| IC50 | 12±n/a nM | ||
| Citation |  Naya, A; Sagara, Y; Ohwaki, K; Saeki, T; Ichikawa, D; Iwasawa, Y; Noguchi, K; Ohtake, N Design, synthesis, and discovery of a novel CCR1 antagonist. J Med Chem44:1429-35 (2001) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| C-C chemokine receptor type 1 | |||
| Name: | C-C chemokine receptor type 1 | ||
| Synonyms: | C-C CKR-1 | CC-CKR-1 | CCR-1 | CCR1_MOUSE | CD_antigen=CD191 | Ccr1 | Cmkbr1 | MIP-1alpha-R | Macrophage inflammatory protein 1-alpha receptor | RANTES-R | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 40904.59 | ||
| Organism: | Mus musculus | ||
| Description: | ChEMBL_1452291 | ||
| Residue: | 355 | ||
| Sequence: |
| ||
| BDBM50098636 | |||
| n/a | |||
| Name | BDBM50098636 | ||
| Synonyms: | 1-Cyclooct-1-enylmethyl-4-[(2,7-dibromo-9H-xanthencarrb0nyl)-amino]-1-ethyl-piperidinium; iodide | CHEMBL289902 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C30H37Br2N2O2 | ||
| Mol. Mass. | 617.434 | ||
| SMILES | CC[N+]1(C\C2=C\CCCCCC2)CCC(CC1)NC(=O)C1c2cc(Br)ccc2Oc2ccc(Br)cc12 |t:4,(7.53,2.69,;6.21,1.9,;6.21,.35,;7.56,-.4,;9.14,.28,;10.55,-.32,;11.96,.28,;12.57,1.69,;11.96,3.14,;10.55,3.72,;9.14,3.12,;8.53,1.69,;4.86,1.11,;3.55,.35,;3.45,-1.39,;4.89,-1.96,;6.24,-1.17,;2.1,-2.16,;.88,-1.17,;.88,.35,;-.44,-1.96,;-1.76,-1.17,;-1.76,.35,;-3.11,1.12,;-3.11,2.69,;-4.46,.35,;-4.42,-1.2,;-3.11,-1.96,;-3.14,-3.5,;-1.79,-4.27,;-1.79,-5.79,;-.47,-6.57,;.88,-5.82,;2.2,-6.59,;.88,-4.28,;-.44,-3.5,)| | ||
| Structure | 
| ||