| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50542172 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1986036 (CHEMBL4619442) |
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| Ki | 1.000000±n/a nM |
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| Citation |  Mallo-Abreu, A; Prieto-Díaz, R; Jespers, W; Azuaje, J; Majellaro, M; Velando, C; García-Mera, X; Caamaño, O; Brea, J; Loza, MI; Gutiérrez-de-Terán, H; Sotelo, E Nitrogen-Walk Approach to Explore Bioisosteric Replacements in a Series of Potent A J Med Chem63:7721-7739 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM50542172 |
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| n/a |
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| Name | BDBM50542172 |
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| Synonyms: | CHEMBL4632760 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H18N4O3 |
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| Mol. Mass. | 338.3605 |
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| SMILES | CC(C)OC(=O)C1=C(C)Nc2nc3ccccc3n2C1c1ncco1 |c:6| |
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| Structure | 
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