| Reaction Details |
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 | Report a problem with these data |
| Target | Matrilysin |
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| Ligand | BDBM50099116 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_105039 |
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| IC50 | >50000±n/a nM |
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| Citation |  Foley, LH; Palermo, R; Dunten, P; Wang, P Novel 5,5-disubstitutedpyrimidine-2,4,6-triones as selective MMP inhibitors. Bioorg Med Chem Lett11:969-72 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Matrilysin |
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| Name: | Matrilysin |
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| Synonyms: | MMP7 | MMP7_HUMAN | MPSL1 | Matrix metalloproteinase 7 | Matrix metalloproteinase-7 (MMP-7) | Matrix metalloproteinase-7 (MMP7) | PUMP1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 29681.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P09237 |
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| Residue: | 267 |
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| Sequence: | MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLK
EMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDL
PHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAF
APGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGD
PQNFKLSQDDIKGIQKLYGKRSNSRKK
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| BDBM50099116 |
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| n/a |
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| Name | BDBM50099116 |
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| Synonyms: | 5-Biphenyl-4-yl-5-hexyl-pyrimidine-2,4,6-trione | CHEMBL175282 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H24N2O3 |
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| Mol. Mass. | 364.4376 |
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| SMILES | CCCCCCC1(C(=O)NC(=O)NC1=O)c1ccc(cc1)-c1ccccc1 |
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| Structure | 
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