| Reaction Details |
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 | Report a problem with these data |
| Target | Elastase |
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| Ligand | BDBM50542709 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1987680 (CHEMBL4621227) |
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| IC50 | 10100±n/a nM |
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| Citation |  Konstantinovi?, J; Yahiaoui, S; Alhayek, A; Haupenthal, J; Schönauer, E; Andreas, A; Kany, AM; Müller, R; Koehnke, J; Berger, FK; Bischoff, M; Hartmann, RW; Brandstetter, H; Hirsch, AKH -Aryl-3-mercaptosuccinimides as Antivirulence Agents Targeting J Med Chem63:8359-8368 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Elastase |
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| Name: | Elastase |
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| Synonyms: | ELAS_PSEAE | Pseudolysin | lasB |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53687.94 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | ChEMBL_619859 |
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| Residue: | 498 |
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| Sequence: | MKKVSTLDLLFVAIMGVSPAAFAADLIDVSKLPSKAAQGAPGPVTLQAAVGAGGADELKA
IRSTTLPNGKQVTRYEQFHNGVRVVGEAITEVKGPGKSVAAQRSGHFVANIAADLPGSTT
AAVSAEQVLAQAKSLKAQGRKTENDKVELVIRLGENNIAQLVYNVSYLIPGEGLSRPHFV
IDAKTGEVLDQWEGLAHAEAGGPGGNQKIGKYTYGSDYGPLIVNDRCEMDDGNVITVDMN
SSTDDSKTTPFRFACPTNTYKQVNGAYSPLNDAHFFGGVVFKLYRDWFGTSPLTHKLYMK
VHYGRSVENAYWDGTAMLFGDGATMFYPLVSLDVAAHEVSHGFTEQNSGLIYRGQSGGMN
EAFSDMAGEAAEFYMRGKNDFLIGYDIKKGSGALRYMDQPSRDGRSIDNASQYYNGIDVH
HSSGVYNRAFYLLANSPGWDTRKAFEVFVDANRYYWTATSNYNSGACGVIRSAQNRNYSA
ADVTRAFSTVGVTCPSAL
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| BDBM50542709 |
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| n/a |
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| Name | BDBM50542709 |
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| Synonyms: | CHEMBL4635838 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H9F2NO2S |
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| Mol. Mass. | 257.256 |
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| SMILES | Fc1ccc(cc1F)N1C(=O)CC(CS)C1=O |
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| Structure | 
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