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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Sigma non-opioid intracellular receptor 1 | ||
| Ligand | BDBM50099800 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_202070 (CHEMBL811340) | ||
| Ki | 28±n/a nM | ||
| Citation |  Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Synthesis and structure-activity relationships of naphthamides as dopamine D3 receptor ligands. J Med Chem44:1815-26 (2001) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Sigma non-opioid intracellular receptor 1 | |||
| Name: | Sigma non-opioid intracellular receptor 1 | ||
| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 25124.85 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q99720 | ||
| Residue: | 223 | ||
| Sequence: |
| ||
| BDBM50099800 | |||
| n/a | |||
| Name | BDBM50099800 | ||
| Synonyms: | 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-adamantan-2-yl-pyrrolidin-3-yl)-amide | CHEMBL52298 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C26H31BrN2O2 | ||
| Mol. Mass. | 483.441 | ||
| SMILES | COc1c(cc(Br)c2ccccc12)C(=O)N[C@H]1CCN(C1)C1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2 |wU:26.29,24.33,22.25,16.17,wD:28.32,TLB:19:21:23:26.30.25,THB:27:28:23:26.30.25,27:26:23:21.28.29,(6.46,-4.73,;7.77,-5.5,;7.81,-7.04,;9.12,-7.81,;9.12,-9.35,;7.81,-10.12,;7.77,-11.66,;6.46,-9.35,;5.14,-10.12,;3.8,-9.35,;3.8,-7.81,;5.14,-7.04,;6.46,-7.81,;10.47,-7.04,;10.44,-5.5,;11.79,-7.81,;13.1,-7,;13.1,-5.5,;15.76,-5.5,;15.76,-7.04,;14.45,-7.77,;17.08,-7.81,;18.27,-6.52,;18.27,-5.05,;19.61,-4.57,;20.99,-5.14,;20.99,-6.68,;19.97,-7.94,;18.55,-7.39,;18.55,-5.79,;19.58,-7,)| | ||
| Structure | 
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