| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M5 |
|---|
| Ligand | BDBM50099893 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_139519 |
|---|
| Ki | >10000±n/a nM |
|---|
| Citation |  Huang, Y; Kegeles, LS; Bae, S; Hwang, D; Roth, BL; Savage, JE; Laruelle, M Synthesis of potent and selective dopamine D(4) antagonists as candidate radioligands. Bioorg Med Chem Lett11:1375-7 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Muscarinic acetylcholine receptor M5 |
|---|
| Name: | Muscarinic acetylcholine receptor M5 |
|---|
| Synonyms: | ACM5_HUMAN | CHRM5 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 60102.35 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1517990 |
|---|
| Residue: | 532 |
|---|
| Sequence: | MEGDSYHNATTVNGTPVNHQPLERHRLWEVITIAAVTAVVSLITIVGNVLVMISFKVNSQ
LKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWALGSLACDLWLALDYVASNASVMN
LLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLISFILWAPAILCWQYLVGKRTVPL
DECQIQFLSEPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSDSVTKAE
KRKPAHRALFRSCLRCPRPTLAQRERNQASWSSSRRSTSTTGKPSQATGPSANWAKAEQL
TTCSSYPSSEDEDKPATDPVLQVVYKSQGKESPGEEFSAEETEETFVKAETEKSDYDTPN
YLLSPAAAHRPKSQKCVAYKFRLVVKADGNQETNNGCHKVKIMPCPFPVAKEPSTKGLNP
NPSHQMTKRKRVVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCDKCVPVTLWHLG
YWLCYVNSTVNPICYALCNRTFRKTFKMLLLCRWKKKKVEEKLYWQGNSKLP
|
|
|
|---|
| BDBM50099893 |
|---|
| n/a |
|---|
| Name | BDBM50099893 |
|---|
| Synonyms: | 3-[4-(4-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine | CHEMBL28997 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H19FN4 |
|---|
| Mol. Mass. | 310.3687 |
|---|
| SMILES | Fc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
