| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase CDC14A |
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| Ligand | BDBM50544427 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1992575 (CHEMBL4626310) |
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| IC50 | >50000±n/a nM |
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| Citation |  Ruddraraju, KV; Aggarwal, D; Niu, C; Baker, EA; Zhang, RY; Wu, L; Zhang, ZY Highly Potent and Selective J Med Chem63:9212-9227 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity protein phosphatase CDC14A |
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| Name: | Dual specificity protein phosphatase CDC14A |
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| Synonyms: | 3.1.3.16 | 3.1.3.48 | CC14A_HUMAN | CDC14 cell division cycle 14 homolog A | CDC14A |
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| Type: | n/a |
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| Mol. Mass.: | 66598.40 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9UNH5 |
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| Residue: | 594 |
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| Sequence: | MAAESGELIGACEFMKDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMV
YRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLS
GSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDF
NWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDA
GFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFT
HAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSEGSINKILSGLD
DMSIGGNLSKTQNMERFGEDNLEDDDVEMKNGITQGDKLRALKSQRQPRTSPSCAFRSDD
TKGHPRAVSQPFRLSSSLQGSAVTLKTSKMALSPSATAKRINRTSLSSGATVRSFSINSR
LASSLGNLNAATDDPENKKTSSSSKAGFTASPFTNLLNGSSQPTTRNYPELNNNQYNRSS
NSNGGNLNSPPGPHSAKTEEHTTILRPSYTGLSSSSARFLSRSIPSLQSEYVHY
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| BDBM50544427 |
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| n/a |
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| Name | BDBM50544427 |
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| Synonyms: | CHEMBL4632818 | US11192850, Entry 4g |
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| Type | Small organic molecule |
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| Emp. Form. | C19H16N2O6 |
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| Mol. Mass. | 368.3401 |
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| SMILES | CN(C)c1cc(O)c(cc1C#Cc1cccc(NC(=O)C(O)=O)c1)C(O)=O |
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| Structure | 
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