| Reaction Details |
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 | Report a problem with these data |
| Target | Receptor-type tyrosine-protein phosphatase epsilon |
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| Ligand | BDBM50544440 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1992583 (CHEMBL4626318) |
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| IC50 | >30000±n/a nM |
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| Citation |  Ruddraraju, KV; Aggarwal, D; Niu, C; Baker, EA; Zhang, RY; Wu, L; Zhang, ZY Highly Potent and Selective J Med Chem63:9212-9227 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Receptor-type tyrosine-protein phosphatase epsilon |
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| Name: | Receptor-type tyrosine-protein phosphatase epsilon |
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| Synonyms: | PTPRE | PTPRE_HUMAN | Protein-tyrosine phosphatase epsilon | Receptor-type tyrosine-protein phosphatase epsilon | Receptor-type tyrosine-protein phosphatase epsilon (PTPε) |
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| Type: | Protein |
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| Mol. Mass.: | 80646.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P23469 |
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| Residue: | 700 |
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| Sequence: | MEPLCPLLLVGFSLPLARALRGNETTADSNETTTTSGPPDPGASQPLLAWLLLPLLLLLL
VLLLAAYFFRFRKQRKAVVSTSDKKMPNGILEEQEQQRVMLLSRSPSGPKKYFPIPVEHL
EEEIRIRSADDCKQFREEFNSLPSGHIQGTFELANKEENREKNRYPNILPNDHSRVILSQ
LDGIPCSDYINASYIDGYKEKNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTNLKERK
EEKCHQYWPDQGCWTYGNIRVCVEDCVVLVDYTIRKFCIQPQLPDGCKAPRLVSQLHFTS
WPDFGVPFTPIGMLKFLKKVKTLNPVHAGPIVVHCSAGVGRTGTFIVIDAMMAMMHAEQK
VDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEYYLYGDTELDVSSLEKHLQTMHGTTTH
FDKIGLEEEFRKLTNVRIMKENMRTGNLPANMKKARVIQIIPYDFNRVILSMKRGQEYTD
YINASFIDGYRQKDYFIATQGPLAHTVEDFWRMIWEWKSHTIVMLTEVQEREQDKCYQYW
PTEGSVTHGEITIEIKNDTLSEAISIRDFLVTLNQPQARQEEQVRVVRQFHFHGWPEIGI
PAEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNILERVKAEGLLDVFQ
AVKSLRLQRPHMVQTLEQYEFCYKVVQDFIDIFSDYANFK
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| BDBM50544440 |
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| n/a |
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| Name | BDBM50544440 |
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| Synonyms: | CHEMBL4647367 | US11192850, Entry 4t |
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| Type | Small organic molecule |
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| Emp. Form. | C17H9ClF3NO3 |
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| Mol. Mass. | 367.706 |
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| SMILES | OC(=O)C(=O)Nc1ccc(cc1)C#Cc1ccc(cc1Cl)C(F)(F)F |
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| Structure | 
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