| Reaction Details |
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 | Report a problem with these data |
| Target | Cholinesterase |
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| Ligand | BDBM50544932 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1993991 (CHEMBL4627886) |
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| IC50 | 8100±n/a nM |
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| Citation |  Xu, Y; Jian, MM; Han, C; Yang, K; Bai, LG; Cao, F; Ma, ZY Design, synthesis and evaluation of new 4-arylthiazole-2-amine derivatives as acetylcholinesterase inhibitors. Bioorg Med Chem Lett30:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholinesterase |
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| Name: | Cholinesterase |
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| Synonyms: | 3.1.1.8 | Acylcholine acylhydrolase | BCHE | Butyrylcholine esterase | CHLE_CANLF | Choline esterase II | Cholinesterase | Pseudocholinesterase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 15084.45 |
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| Organism: | Canis lupus familiaris |
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| Description: | ChEMBL_119907 |
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| Residue: | 141 |
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| Sequence: | NTDQSFPGFPGSEMWNPNTDLSEDCLYLNVWIPTPKPKNATVMIWIYGGGFQTGTSSLPV
YDGKFLARVERVIVVSVNYRVGALGFLALPGNPEAPGNLGLFDQQLALQWVQKNIAAFGG
NPKSVTLFGESAGAGSVGLHL
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| BDBM50544932 |
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| n/a |
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| Name | BDBM50544932 |
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| Synonyms: | CHEMBL4634668 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H29N3O4S |
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| Mol. Mass. | 467.58 |
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| SMILES | COc1ccc(cc1OC)C(=O)Nc1ncc(s1)-c1ccc(OCCCN2CCCC2)cc1 |
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| Structure | 
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