| Reaction Details |
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 | Report a problem with these data |
| Target | Tubulin beta-2B chain |
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| Ligand | BDBM50102423 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_225807 (CHEMBL845247) |
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| IC50 | 3600±n/a nM |
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| Citation |  Mu, F; Coffing, SL; Riese, DJ; Geahlen, RL; Verdier-Pinard, P; Hamel, TE; Johnson, J; Cushman, M Design, synthesis, and biological evaluation of a series of lavendustin A analogues that inhibit EGFR and Syk tyrosine kinases, as well as tubulin polymerization. J Med Chem44:441-52 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Tubulin beta-2B chain |
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| Name: | Tubulin beta-2B chain |
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| Synonyms: | TBB2B_BOVIN | TUBB2B | Tubulin | Tubulin beta chain |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49932.38 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_211651 |
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| Residue: | 445 |
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| Sequence: | MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYV
PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV
RKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVV
EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMM
AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG
LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
EYQQYQDATADEQGEFEEEEGEDEA
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| BDBM50102423 |
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| n/a |
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| Name | BDBM50102423 |
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| Synonyms: | 5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-N-phenethyl-benzamide | CHEMBL137924 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22N2O4 |
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| Mol. Mass. | 378.4211 |
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| SMILES | Oc1ccc(O)c(CNc2ccc(O)c(c2)C(=O)NCCc2ccccc2)c1 |
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| Structure | 
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