| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-synuclein |
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| Ligand | BDBM50545088 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1994333 (CHEMBL4628228) |
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| Kd | 8.2±n/a nM |
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| Citation |  Chen, YF; Bian, J; Zhang, P; Bu, LL; Shen, Y; Yu, WB; Lu, XH; Lin, X; Ye, DY; Wang, J; Chu, Y Design, synthesis and identification of N, N-dibenzylcinnamamide (DBC) derivatives as novel ligands for ?-synuclein fibrils by SPR evaluation system. Bioorg Med Chem28:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-synuclein |
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| Name: | Alpha-synuclein |
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| Synonyms: | NACP | PARK1 | SNCA | SYUA_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 14451.42 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P37840 |
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| Residue: | 140 |
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| Sequence: | MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK
EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDP
DNEAYEMPSEEGYQDYEPEA
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| BDBM50545088 |
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| n/a |
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| Name | BDBM50545088 |
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| Synonyms: | CHEMBL4633757 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H17N3O4 |
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| Mol. Mass. | 387.3881 |
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| SMILES | [O-][N+](=O)c1ccccc1CN(Cc1ccco1)C(=O)\C=C\c1ccc(cc1)C#N |
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| Structure | 
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