Reaction Details |
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Target | Alpha-synuclein |
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Ligand | BDBM50545092 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1994333 (CHEMBL4628228) |
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Kd | 107±n/a nM |
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Citation | Chen, YF; Bian, J; Zhang, P; Bu, LL; Shen, Y; Yu, WB; Lu, XH; Lin, X; Ye, DY; Wang, J; Chu, Y Design, synthesis and identification of N, N-dibenzylcinnamamide (DBC) derivatives as novel ligands for ?-synuclein fibrils by SPR evaluation system. Bioorg Med Chem28:0 (2020) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Alpha-synuclein |
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Name: | Alpha-synuclein |
Synonyms: | NACP | PARK1 | SNCA | SYUA_HUMAN |
Type: | Protein |
Mol. Mass.: | 14451.42 |
Organism: | Homo sapiens (Human) |
Description: | P37840 |
Residue: | 140 |
Sequence: | MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK
EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDP
DNEAYEMPSEEGYQDYEPEA
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BDBM50545092 |
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n/a |
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Name | BDBM50545092 |
Synonyms: | CHEMBL4642469 |
Type | Small organic molecule |
Emp. Form. | C24H20N2O |
Mol. Mass. | 352.4284 |
SMILES | O=C(\C=C\c1ccc(cc1)C#N)N(Cc1ccccc1)Cc1ccccc1 |
Structure |
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