| Reaction Details |
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 | Report a problem with these data |
| Target | Histone-lysine N-methyltransferase SETD7 |
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| Ligand | BDBM50545364 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1994888 (CHEMBL4628783) |
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| IC50 | 23000±n/a nM |
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| Citation |  Hou, Z; Min, W; Zhang, R; Niu, A; Li, Y; Cao, L; Han, J; Luo, C; Yang, P; Ding, H Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small-molecule inhibitors. Bioorg Med Chem Lett30:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone-lysine N-methyltransferase SETD7 |
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| Name: | Histone-lysine N-methyltransferase SETD7 |
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| Synonyms: | Histone-lysine N-methyltransferase SETD7 | KIAA1717 | KMT7 | SET domain-containing protein 7/9 (Set7/9) | SET7 | SET9 | SETD7 | SETD7_HUMAN |
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| Type: | Enzyme |
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| Mol. Mass.: | 40691.12 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8WTS6 |
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| Residue: | 366 |
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| Sequence: | MDSDDEMVEEAVEGHLDDDGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLE
GYYVDDALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCW
IYYPDGGSLVGEVNEDGEMTGEKIAYVYPDERTALYGKFIDGEMIEGKLATLMSTEEGRP
HFELMPGNSVYHFDKSTSSCISTNALLPDPYESERVYVAESLISSAGEGLFSKVAVGPNT
VMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEPYNHVSKYCASLGHKANHSFT
PNCIYDMFVHPRFGPIKCIRTLRAVEADEELTVAYGYDHSPPGKSGPEAPEWYQVELKAF
QATQQK
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| BDBM50545364 |
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| n/a |
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| Name | BDBM50545364 |
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| Synonyms: | CHEMBL4639453 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H18N2O5S |
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| Mol. Mass. | 374.411 |
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| SMILES | CS(=O)(=O)N1CCN(CC1)C(=O)c1ccc(cc1)C1=CC(=O)C=CC1=O |c:24,t:20| |
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| Structure | 
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