| Reaction Details |
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 | Report a problem with these data |
| Target | Tryptase beta-2 |
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| Ligand | BDBM50103805 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_210702 |
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| Ki | 7000±n/a nM |
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| Citation |  Dener, JM; Wang, VR; Rice, KD; Gangloff, AR; Kuo, EY; Newcomb, WS; Putnam, D; Wong, M Monocharged inhibitors of mast cell tryptase derived from potent and selective dibasic inhibitors. Bioorg Med Chem Lett11:2325-30 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Tryptase beta-2 |
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| Name: | Tryptase beta-2 |
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| Synonyms: | TPS2 | TPSB2 | TRYB2_HUMAN | Tryptase | Tryptase II | Tryptase beta-1 | Tryptase-2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 30518.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_210702 |
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| Residue: | 275 |
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| Sequence: | MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCG
GSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGA
DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV
PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAG
VVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP
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| BDBM50103805 |
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| n/a |
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| Name | BDBM50103805 |
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| Synonyms: | 4-[2-(4-Guanidino-phenyl)-acetyl]-piperazine-1-carboxylic acid (3,3-diphenyl-propyl)-amide | CHEMBL310411 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H34N6O2 |
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| Mol. Mass. | 498.6193 |
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| SMILES | [#7]\[#6](-[#7])=[#7]/c1ccc(-[#6]-[#6](=O)-[#7]-2-[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](=O)-[#7]-[#6]-[#6]-[#6](-c2ccccc2)-c2ccccc2)cc1 |
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| Structure | 
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