| Reaction Details |
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 | Report a problem with these data |
| Target | Bromodomain-containing protein 9 |
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| Ligand | BDBM50504160 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1998150 (CHEMBL4650007) |
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| IC50 | 701±n/a nM |
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| Citation |  Picaud, S; Leonards, K; Lambert, JP; Dovey, O; Wells, C; Fedorov, O; Monteiro, O; Fujisawa, T; Wang, CY; Lingard, H; Tallant, C; Nikbin, N; Guetzoyan, L; Ingham, R; Ley, SV; Brennan, P; Muller, S; Samsonova, A; Gingras, AC; Schwaller, J; Vassiliou, G; Knapp, S; Filippakopoulos, P Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia. Sci Adv2:0 (2016) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Bromodomain-containing protein 9 |
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| Name: | Bromodomain-containing protein 9 |
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| Synonyms: | BRD9 | BRD9_HUMAN | Bromodomain-containing protein 9 | Rhabdomyosarcoma antigen MU-RMS-40.8 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66994.30 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_108000 |
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| Residue: | 597 |
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| Sequence: | MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHER
ERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEP
PPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHP
MDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKQ
AALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSLTDSTAEEHVL
ALVEHAADEARDRINRFLPGGKMGYLKRNGDGSLLYSVVNTAEPDADEEETHPVDLSSLS
SKLLPGFTTLGFKDERRNKVTFLSSATTALSMQNNSVFGDLKSDEMELLYSAYGDETGVQ
CALSLQEFVKDAGSYSKKVVDDLLDQITGGDHSRTLFQLKQRRNVPMKPPDEAKVGDTLG
DSSSSVLEFMSMKSYPDVSVDISMLSSLGKVKKELDPDDSHLNLDETTKLLQDLHEAQAE
RGGSRPSSNLSSLSNASERDQHHLGSPSRLSVGEQPDVTHDPYEFLQSPEPAASAKT
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| BDBM50504160 |
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| n/a |
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| Name | BDBM50504160 |
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| Synonyms: | CHEMBL3133807 | US11773085, Compound B25 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H20N6O4S |
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| Mol. Mass. | 404.444 |
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| SMILES | CCOC(=O)Nc1cc(nn2c(C)nnc12)-c1ccc(C)c(NS(C)(=O)=O)c1 |
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| Structure | 
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