| Reaction Details |
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 | Report a problem with these data |
| Target | Phosphoglycerate mutase 1 |
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| Ligand | BDBM50266303 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2012780 (CHEMBL4666358) |
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| IC50 | 140±n/a nM |
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| Citation |  Huang, K; Jiang, L; Liang, R; Li, H; Ruan, X; Shan, C; Ye, D; Zhou, L Synthesis and biological evaluation of anthraquinone derivatives as allosteric phosphoglycerate mutase 1 inhibitors for cancer treatment. Eur J Med Chem168:45-57 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Phosphoglycerate mutase 1 |
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| Name: | Phosphoglycerate mutase 1 |
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| Synonyms: | BPG-dependent PGAM 1 | PGAM-B | PGAM1 | PGAM1_HUMAN | PGAMA | Phosphoglycerate mutase 1 | Phosphoglycerate mutase isozyme B |
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| Type: | PROTEIN |
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| Mol. Mass.: | 28806.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109479 |
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| Residue: | 254 |
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| Sequence: | MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQ
KRAIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD
VPPPPMEPDHPFYSNISKDRRYADLTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKR
VLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVR
KAMEAVAAQGKAKK
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| BDBM50266303 |
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| n/a |
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| Name | BDBM50266303 |
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| Synonyms: | CHEMBL4763924 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H16ClNO6S |
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| Mol. Mass. | 505.926 |
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| SMILES | Oc1c(O)c2C(=O)c3ccccc3C(=O)c2cc1NS(=O)(=O)c1ccc(cc1)-c1ccc(Cl)cc1 |
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| Structure | 
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