| Reaction Details |
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 | Report a problem with these data |
| Target | Complement factor D |
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| Ligand | BDBM203864 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2014999 (CHEMBL4668577) |
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| IC50 | >30000±n/a nM |
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| Citation |  Cheng, KJ; Hsieh, CM; Nepali, K; Liou, JP Ocular Disease Therapeutics: Design and Delivery of Drugs for Diseases of the Eye. J Med Chem63:10533-10593 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Complement factor D |
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| Name: | Complement factor D |
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| Synonyms: | Adipsin | C3 convertase activator | CFAD_HUMAN | CFD | DF | PFD | Properdin factor D |
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| Type: | Protein |
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| Mol. Mass.: | 27039.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00746 |
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| Residue: | 253 |
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| Sequence: | MHSWERLAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQW
VLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQL
SEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCN
RRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTR
VASYAAWIDSVLA
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| BDBM203864 |
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| n/a |
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| Name | BDBM203864 |
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| Synonyms: | (S)-N2-(4-methoxyphenethyl)-N1-(naphthalen-1-ylmethyl)pyrrolidine-1,2-dicarboxamide (1) |
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| Type | Small organic molecule |
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| Emp. Form. | C26H29N3O3 |
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| Mol. Mass. | 431.5268 |
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| SMILES | COc1ccc(CCNC(=O)[C@@H]2CCCN2C(=O)NCc2cccc3ccccc23)cc1 |r| |
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| Structure | 
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