| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Complement factor D |
|---|
| Ligand | BDBM50546245 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2015002 (CHEMBL4668580) |
|---|
| Kd | >30000±n/a nM |
|---|
| Citation |  Cheng, KJ; Hsieh, CM; Nepali, K; Liou, JP Ocular Disease Therapeutics: Design and Delivery of Drugs for Diseases of the Eye. J Med Chem63:10533-10593 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Complement factor D |
|---|
| Name: | Complement factor D |
|---|
| Synonyms: | Adipsin | C3 convertase activator | CFAD_HUMAN | CFD | DF | PFD | Properdin factor D |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 27039.19 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P00746 |
|---|
| Residue: | 253 |
|---|
| Sequence: | MHSWERLAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQW
VLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQL
SEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCN
RRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTR
VASYAAWIDSVLA
|
|
|
|---|
| BDBM50546245 |
|---|
| n/a |
|---|
| Name | BDBM50546245 |
|---|
| Synonyms: | CHEMBL4101312 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H14N2O2 |
|---|
| Mol. Mass. | 266.2946 |
|---|
| SMILES | NC(=O)c1cc2cc(OCc3ccccc3)ccc2[nH]1 |
|---|
| Structure | 
|
|---|
Search and Browse
