| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1A |
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| Ligand | BDBM50101814 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2016248 (CHEMBL4669826) |
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| Ki | 2500±n/a nM |
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| Citation |  Bieszczad, B; Siwek, A; Wilczek, M; Trzybi?ski, D; Wo?niak, K; Sata?a, G; Bojarski, AJ; Mieczkowski, A Synthesis, crystal structure and biological activity of novel analogues of tricyclic drugs. Bioorg Med Chem Lett30:127493 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1A |
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| Name: | 5-hydroxytryptamine receptor 1A |
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| Synonyms: | 5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A |
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| Type: | n/a |
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| Mol. Mass.: | 46122.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 422 |
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| Sequence: | MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
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| BDBM50101814 |
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| n/a |
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| Name | BDBM50101814 |
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| Synonyms: | Dibenzepin |
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| Type | Small organic molecule |
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| Emp. Form. | C18H21N3O |
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| Mol. Mass. | 295.3788 |
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| SMILES | CN(C)CCN1c2ccccc2N(C)c2ccccc2C1=O |
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| Structure | 
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