| Reaction Details |
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 | Report a problem with these data |
| Target | Apoptosis regulator BAX |
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| Ligand | BDBM50547487 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2018355 (CHEMBL4671933) |
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| EC50 | 725±n/a nM |
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| Citation |  Liang, T; Zhou, Y; Elhassan, RM; Hou, X; Yang, X; Fang, H HDAC-Bax Multiple Ligands Enhance Bax-Dependent Apoptosis in HeLa Cells. J Med Chem63:12083-12099 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Apoptosis regulator BAX |
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| Name: | Apoptosis regulator BAX |
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| Synonyms: | Apoptosis regulator BAX | BAX | BAX_HUMAN | BCL2L4 | Bcl-2-like protein 4 | Bcl2-L-4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 21181.15 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_100916 |
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| Residue: | 192 |
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| Sequence: | MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS
ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL
VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGV
LTASLTIWKKMG
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| BDBM50547487 |
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| n/a |
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| Name | BDBM50547487 |
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| Synonyms: | CHEMBL4761391 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H21N7O4S2 |
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| Mol. Mass. | 547.609 |
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| SMILES | ONC(=O)CCCOc1ccc(cc1)-c1csc(n1)N1N=C(\C(=N\Nc2nccs2)C1=O)c1ccccc1 |c:22| |
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| Structure | 
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