| Reaction Details |
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 | Report a problem with these data |
| Target | Macrophage migration inhibitory factor |
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| Ligand | BDBM50240404 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2018482 (CHEMBL4672060) |
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| Kd | 1400±n/a nM |
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| Citation |  Cirillo, PF; Asojo, OA; Khire, U; Lee, Y; Mootien, S; Hegan, P; Sutherland, AG; Peterson-Roth, E; Ledizet, M; Koski, RA; Anthony, KG Inhibition of Macrophage Migration Inhibitory Factor by a Chimera of Two Allosteric Binders. ACS Med Chem Lett11:1843-1847 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Macrophage migration inhibitory factor |
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| Name: | Macrophage migration inhibitory factor |
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| Synonyms: | GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase |
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| Type: | Enzyme |
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| Mol. Mass.: | 12478.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14174 |
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| Residue: | 115 |
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| Sequence: | MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALC
SLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
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| BDBM50240404 |
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| n/a |
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| Name | BDBM50240404 |
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| Synonyms: | (Ibudilast)1-(2-Isopropyl-pyrazolo[1,5-a]pyridin-3-yl)-2-methyl-propan-1-one | 1-(2-isopropylH-pyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-one | CHEMBL19449 | IBUDILAST |
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| Type | Small organic molecule |
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| Emp. Form. | C14H18N2O |
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| Mol. Mass. | 230.3055 |
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| SMILES | CC(C)C(=O)c1c(nn2ccccc12)C(C)C |
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| Structure | 
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