| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP2 subtype |
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| Ligand | BDBM50106548 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_158299 (CHEMBL763184) |
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| IC50 | >10000±n/a nM |
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| Citation |  Soper, DL; Milbank, JB; Mieling, GE; Dirr, MJ; Kende, AS; Cooper, R; Jee, WS; Yao, W; Chen, JL; Bodman, M; Lundy, MW; De, B; Stella, ME; Ebetino, FH; Wang, Y; deLong, MA; Wos, JA Synthesis and biological evaluation of prostaglandin-F alkylphosphinic acid derivatives as bone anabolic agents for the treatment of osteoporosis. J Med Chem44:4157-69 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP2 subtype |
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| Name: | Prostaglandin E2 receptor EP2 subtype |
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| Synonyms: | PE2R2_HUMAN | PGE receptor EP2 subtype | PTGER2 | Prostaglandin E2 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP4 subtype | Prostanoid EP2 Receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 39775.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43116 |
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| Residue: | 358 |
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| Sequence: | MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR
RSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFS
LATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQ
YCPGTWCFIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGS
GRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRKEKWDLQA
LRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSDASKQADL
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| BDBM50106548 |
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| n/a |
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| Name | BDBM50106548 |
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| Synonyms: | CHEMBL440164 | {6-[3,5-Dihydroxy-2-(3-hydroxy-4-phenoxy-but-1-enyl)-cyclopentyl]-hex-4-enyl}-methyl-phosphinic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C22H33O6P |
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| Mol. Mass. | 424.4676 |
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| SMILES | CP(O)(=O)CCCC=CC[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)COc1ccccc1 |w:7.6| |
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| Structure | 
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