| Reaction Details |
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 | Report a problem with these data |
| Target | Papain |
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| Ligand | BDBM22857 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_152640 |
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| IC50 | 91000±n/a nM |
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| Citation |  Singh, SB; Graham, PL; Reamer, RA; Cordingley, MG Discovery, total synthesis, HRV 3C-protease inhibitory activity, and structure-activity relationships of 2-methoxystypandrone and its analogues. Bioorg Med Chem Lett11:3143-6 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Papain |
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| Name: | Papain |
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| Synonyms: | Allergen=Car p 1 | PAPA1_CARPA | PPI | Papaya proteinase I |
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| Type: | Enzyme |
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| Mol. Mass.: | 38923.01 |
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| Organism: | Carica papaya |
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| Description: | Papain was purchased from Sigma, Germany. |
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| Residue: | 345 |
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| Sequence: | MAMIPSISKLLFVAICLFVYMGLSFGDFSIVGYSQNDLTSTERLIQLFESWMLKHNKIYK
NIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTE
LSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNE
YSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKT
DGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYG
PNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
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| BDBM22857 |
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| n/a |
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| Name | BDBM22857 |
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| Synonyms: | 1,2-Dione-Based Compound, 14 | 9,10-dihydrophenanthrene-9,10-dione | CHEMBL51931 | Phenanthrene-9,10 dione | cid_6763 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H8O2 |
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| Mol. Mass. | 208.2121 |
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| SMILES | O=C1C(=O)c2ccccc2-c2ccccc12 |
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| Structure | 
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