| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
|---|
| Ligand | BDBM50108306 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_2675 |
|---|
| Ki | 15±n/a nM |
|---|
| Citation |  Chang-Fong, J; Addo, J; Dukat, M; Smith, C; Mitchell, NA; Herrick-Davis, K; Teitler, M; Glennon, RA Evaluation of isotryptamine derivatives at 5-HT(2) serotonin receptors. Bioorg Med Chem Lett12:155-8 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 2A |
|---|
| Name: | 5-hydroxytryptamine receptor 2A |
|---|
| Synonyms: | 5-HT-2A | 5-HT2 | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_RAT | Htr2 | Htr2a | Serotonin Receptor 2A |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 52852.05 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | Rat cortex membranes 5-HT2A receptors. |
|---|
| Residue: | 471 |
|---|
| Sequence: | MEILCEDNISLSSIPNSLMQLGDGPRLYHNDFNSRDANTSEASNWTIDAENRTNLSCEGY
LPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAIWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPALAYK
SSQLQVGQKKNSQEDAEQTVDDCSMVTLGKQQSEENCTDNIETVNEKVSCV
|
|
|
|---|
| BDBM50108306 |
|---|
| n/a |
|---|
| Name | BDBM50108306 |
|---|
| Synonyms: | (S)-1-(5,6-difluoro-1H-indol-1-yl)propan-2-amine | (S)-2-(5,6-Difluoro-indol-1-yl)-1-methyl-ethylamine | CHEMBL40726 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H12F2N2 |
|---|
| Mol. Mass. | 210.2232 |
|---|
| SMILES | C[C@H](N)Cn1ccc2cc(F)c(F)cc12 |
|---|
| Structure | 
|
|---|
Search and Browse
