| Reaction Details |
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 | Report a problem with these data |
| Target | DNA polymerase beta |
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| Ligand | BDBM50109029 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_50295 (CHEMBL660415) |
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| Ki | 20100±n/a nM |
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| Citation |  Watanabe, M; Hanashima, S; Mizushina, Y; Yoshida, H; Oshige, M; Sakaguchi, K; Sugawara, F Biotinylated lithocholic acids for affinity chromatography of mammalian DNA polymerases alpha and beta. Bioorg Med Chem Lett12:287-90 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| DNA polymerase beta |
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| Name: | DNA polymerase beta |
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| Synonyms: | DNA Polymerase beta | DPOLB_RAT | Polb |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38334.34 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1361926 |
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| Residue: | 335 |
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| Sequence: | MSKRKAPQETLNGGITDMLVELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVTGIGPSAARKLVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFEDFEKRIPREEMLQMQDIVLNEVKKLDPEYIATVCGS
FRRGAESSGDMDVLLTHPNFTSESSKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQ
LPSENDENEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEQDIFDYIQWRYREPKDRSE
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| BDBM50109029 |
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| n/a |
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| Name | BDBM50109029 |
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| Synonyms: | 4-{10,13-Dimethyl-3-[3-(6-{6-[5-(2-oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoylamino]-hexanoylamino}-hexanoylamino)-propionyloxy]-hexadecahydro-cyclopenta[a]phenanthren-17-yl}-pentanoic acid | CHEMBL3137892 |
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| Type | Small organic molecule |
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| Emp. Form. | C49H81N5O8S |
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| Mol. Mass. | 900.261 |
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| SMILES | [H][C@@](C)(CCC(O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CCC4C[C@H](CC[C@]4(C)[C@@]3([H])CC[C@]12C)OC(=O)CCNC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCCC1SCC2NC(=O)NC12 |
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| Structure | 
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