| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Amphiregulin |
|---|
| Ligand | BDBM50291707 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_217975 (CHEMBL824094) |
|---|
| IC50 | 470±n/a nM |
|---|
| Citation |  Sawa, M; Tsukamoto, T; Kiyoi, T; Kurokawa, K; Nakajima, F; Nakada, Y; Yokota, K; Inoue, Y; Kondo, H; Yoshino, K New strategy for antedrug application: development of metalloproteinase inhibitors as antipsoriatic drugs. J Med Chem45:930-6 (2002) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Amphiregulin |
|---|
| Name: | Amphiregulin |
|---|
| Synonyms: | AREG | AREGB | AREG_HUMAN | SDGF |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 27898.07 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_217975 |
|---|
| Residue: | 252 |
|---|
| Sequence: | MRAPLLPPAPVVLSLLILGSGHYAAGLDLNDTYSGKREPFSGDHSADGFEVTSRSEMSSG
SEISPVSEMPSSSEPSSGADYDYSEEYDNEPQIPGYIVDDSVRVEQVVKPPQNKTESENT
SDKPKRKKKGGKNGKNRRNRKKKNPCNAEFQNFCIHGECKYIEHLEAVTCKCQQEYFGER
CGEKSMKTHSMIDSSLSKIALAAIAAFMSAVILTAVAVITVQLRRQYVRKYEGEAEERKK
LRQENGNVHAIA
|
|
|
|---|
| BDBM50291707 |
|---|
| n/a |
|---|
| Name | BDBM50291707 |
|---|
| Synonyms: | (S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 2-fluoro-ethyl ester | CHEMBL347021 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H22FN2O5P |
|---|
| Mol. Mass. | 408.3605 |
|---|
| SMILES | COc1ccc(cc1)[P@@](=O)(OCCF)N1Cc2ccccc2C[C@@H]1C(=O)NO |
|---|
| Structure | 
|
|---|
Search and Browse
