| Reaction Details |
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 | Report a problem with these data |
| Target | DNA polymerase I, thermostable |
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| Ligand | BDBM50111321 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_209735 |
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| IC50 | >10000±n/a nM |
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| Citation |  Alberti, P; Schmitt, P; Nguyen, CH; Rivalle, C; Hoarau, M; Grierson, DS; Mergny, JL Benzoindoloquinolines interact with DNA tetraplexes and inhibit telomerase. Bioorg Med Chem Lett12:1071-4 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| DNA polymerase I, thermostable |
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| Name: | DNA polymerase I, thermostable |
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| Synonyms: | DNA polymerase I, thermostable | DPO1_THEAQ | Taq polymerase 1 | pol1 | polA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 93906.95 |
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| Organism: | Thermus aquaticus |
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| Description: | ChEMBL_1289218 |
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| Residue: | 832 |
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| Sequence: | MRGMLPLFEPKGRVLLVDGHHLAYRTFHALKGLTTSRGEPVQAVYGFAKSLLKALKEDGD
AVIVVFDAKAPSFRHEAYGGYKAGRAPTPEDFPRQLALIKELVDLLGLARLEVPGYEADD
VLASLAKKAEKEGYEVRILTADKDLYQLLSDRIHVLHPEGYLITPAWLWEKYGLRPDQWA
DYRALTGDESDNLPGVKGIGEKTARKLLEEWGSLEALLKNLDRLKPAIREKILAHMDDLK
LSWDLAKVRTDLPLEVDFAKRREPDRERLRAFLERLEFGSLLHEFGLLESPKALEEAPWP
PPEGAFVGFVLSRKEPMWADLLALAAARGGRVHRAPEPYKALRDLKEARGLLAKDLSVLA
LREGLGLPPGDDPMLLAYLLDPSNTTPEGVARRYGGEWTEEAGERAALSERLFANLWGRL
EGEERLLWLYREVERPLSAVLAHMEATGVRLDVAYLRALSLEVAEEIARLEAEVFRLAGH
PFNLNSRDQLERVLFDELGLPAIGKTEKTGKRSTSAAVLEALREAHPIVEKILQYRELTK
LKSTYIDPLPDLIHPRTGRLHTRFNQTATATGRLSSSDPNLQNIPVRTPLGQRIRRAFIA
EEGWLLVALDYSQIELRVLAHLSGDENLIRVFQEGRDIHTETASWMFGVPREAVDPLMRR
AAKTINFGVLYGMSAHRLSQELAIPYEEAQAFIERYFQSFPKVRAWIEKTLEEGRRRGYV
ETLFGRRRYVPDLEARVKSVREAAERMAFNMPVQGTAADLMKLAMVKLFPRLEEMGARML
LQVHDELVLEAPKERAEAVARLAKEVMEGVYPLAVPLEVEVGIGEDWLSAKE
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| BDBM50111321 |
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| n/a |
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| Name | BDBM50111321 |
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| Synonyms: | CHEMBL10763 | N'-(11-Methoxy-13H-5,13-diaza-dibenzo[a,i]fluoren-6-yl)-N,N-dimethyl-ethane-1,2-diamine |
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| Type | Small organic molecule |
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| Emp. Form. | C24H24N4O |
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| Mol. Mass. | 384.4736 |
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| SMILES | COc1ccc2ccc3c([nH]c4c3c(NCCN(C)C)nc3ccccc43)c2c1 |
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| Structure | 
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