| Reaction Details |
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 | Report a problem with these data |
| Target | Ectonucleoside triphosphate diphosphohydrolase 1 |
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| Ligand | BDBM18136 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2034691 (CHEMBL4688849) |
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| IC50 | >100000±n/a nM |
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| Citation |  Wang, Y; Wang, C; Zhu, Y; Zhang, Y; Chen, B; Wu, Y; Yao, J; Miao, Z Discovery of natural product ellagic acid as a potent CD73 and CD39 dual inhibitor. Bioorg Med Chem Lett34:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Ectonucleoside triphosphate diphosphohydrolase 1 |
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| Name: | Ectonucleoside triphosphate diphosphohydrolase 1 |
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| Synonyms: | 3.6.1.5 | CD_antigen=CD39 | Cd39 | ENTP1_MOUSE | Ecto-ATP diphosphohydrolase 1 | Ecto-ATPDase 1 | Ecto-ATPase 1 | Ecto-apyrase | Ectonucleoside triphosphate diphosphohydrolase 1 | Entpd1 | Lymphoid cell activation antigen | NTPDase 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57200.10 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_120146 |
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| Residue: | 510 |
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| Sequence: | MEDIKDSKVKRFCSKNILIILGFTSILAVIALIAVGLTQNKPLPENVKYGIVLDAGSSHT
NLYIYKWPAEKENDTGVVQQLEECQVKGPGISKYAQKTDEIGAYLAECMELSTELIPTSK
HHQTPVYLGATAGMRLLRMESEQSADEVLAAVSTSLKSYPFDFQGAKIITGQEEGAYGWI
TINYLLGRFTQEQSWLSLISDSQKQETFGALDLGGASTQITFVPQNSTIESPENSLQFRL
YGEDYTVYTHSFLCYGKDQALWQKLAKDIQVSSGGVLKDPCFNPGYEKVVNVSELYGTPC
TKRFEKKLPFDQFRIQGTGDYEQCHQSILELFNNSHCPYSQCAFNGVFLPPLHGSFGAFS
AFYFVMDFFKKVAKNSVISQEKMTEITKNFCSKSWEETKTSYPSVKEKYLSEYCFSGAYI
LSLLQGYNFTDSSWEQIHFMGKIKDSNAGWTLGYMLNLTNMIPAEQPLSPPLPHSTYIGL
MVLFSLLLVAVAITGLFIYSKPSYFWKEAV
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| BDBM18136 |
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| n/a |
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| Name | BDBM18136 |
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| Synonyms: | ADP, alpha beta-me | AMPCPP | [({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)methyl]phosphonic acid | alpha, beta-methyleneadenosine 5 -diphosphate | cid_92199 |
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| Type | Nucleoside or nucleotide |
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| Emp. Form. | C11H17N5O9P2 |
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| Mol. Mass. | 425.2283 |
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| SMILES | Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)CP(O)(O)=O)[C@@H](O)[C@H]1O |r| |
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| Structure | 
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