| Reaction Details |
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 | Report a problem with these data |
| Target | Arginase-1 |
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| Ligand | BDBM50008099 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2045304 (CHEMBL4700003) |
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| IC50 | 6000±n/a nM |
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| Citation |  Muller, J; Cardey, B; Zedet, A; Desingle, C; Grzybowski, M; Pomper, P; Foley, S; Harakat, D; Ramseyer, C; Girard, C; Pudlo, M Synthesis, evaluation and molecular modelling of piceatannol analogues as arginase inhibitors. RSC Med Chem11:559-568 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Arginase-1 |
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| Name: | Arginase-1 |
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| Synonyms: | ARG1 | ARGI1_HUMAN | Liver-type arginase | Type I arginase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 34737.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_978893 |
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| Residue: | 322 |
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| Sequence: | MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN
DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV
IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR
DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF
TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT
LACFGLAREGNHKPIDYLNPPK
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| BDBM50008099 |
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| n/a |
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| Name | BDBM50008099 |
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| Synonyms: | CHEMBL1234777 |
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| Type | Small organic molecule |
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| Emp. Form. | C5H12N4O3 |
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| Mol. Mass. | 176.1738 |
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| SMILES | N[C@@H](CCNC(=N)NO)C(O)=O |r| |
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| Structure | 
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