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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Mitogen-activated protein kinase 6 | ||
| Ligand | BDBM50553823 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_2047482 (CHEMBL4702181) | ||
| Kd | 5600±n/a nM | ||
| Citation |  Grädler, U; Busch, M; Leuthner, B; Raba, M; Burgdorf, L; Lehmann, M; Linde, N; Esdar, C Biochemical, cellular and structural characterization of novel and selective ERK3 inhibitors. Bioorg Med Chem Lett30:0 (2020) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Mitogen-activated protein kinase 6 | |||
| Name: | Mitogen-activated protein kinase 6 | ||
| Synonyms: | ERK3 | MAPK6 | MK06_HUMAN | PRKM6 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 82643.07 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_774367 | ||
| Residue: | 721 | ||
| Sequence: |
| ||
| BDBM50553823 | |||
| n/a | |||
| Name | BDBM50553823 | ||
| Synonyms: | CHEMBL4764076 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C18H22N6O2 | ||
| Mol. Mass. | 354.4063 | ||
| SMILES | COc1ccc(cc1)-n1nnc2cnc(N[C@H]3CC[C@H](CO)CC3)nc12 |r,wU:19.20,wD:16.16,(62.74,-29.24,;61.24,-29.57,;60.77,-31.04,;61.81,-32.18,;61.34,-33.65,;59.83,-33.96,;58.8,-32.84,;59.26,-31.38,;59.37,-35.43,;60.28,-36.67,;59.38,-37.93,;57.91,-37.46,;56.57,-38.24,;55.24,-37.47,;55.24,-35.92,;53.91,-35.15,;53.91,-33.61,;55.24,-32.85,;55.25,-31.32,;53.92,-30.54,;53.92,-29,;52.59,-28.23,;52.58,-31.31,;52.58,-32.85,;56.57,-35.15,;57.9,-35.92,)| | ||
| Structure | 
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