| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM50115620 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_35527 (CHEMBL649553) |
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| Ki | 150±n/a nM |
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| Citation |  Powers, RA; Shoichet, BK Structure-based approach for binding site identification on AmpC beta-lactamase. J Med Chem45:3222-34 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | AMPC_ECOLI | Beta-lactamase | Beta-lactamase (AmpC) | Beta-lactamase AmpC | Cephalosporinase | Escherichia coli K-12 | ampA | ampC |
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| Type: | Protien |
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| Mol. Mass.: | 41561.62 |
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| Organism: | Escherichia coli |
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| Description: | P00811 |
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| Residue: | 377 |
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| Sequence: | MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWG
YADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPTTKYWPELTAKQWNGI
TLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVK
PSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVK
STIEDMARWVQSNLKPLDINEKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSII
NGSDNKIALAARPVKAITPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNY
PNPARVDAAWQILNALQ
|
|
|
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| BDBM50115620 |
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| n/a |
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| Name | BDBM50115620 |
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| Synonyms: | 3-(2-Chloro-phenyl)-5-methyl-2,3-dihydro-isoxazole-4-carboxylic acid dihydroxyboranylmethyl-amide | Acylglycineboronic acid, 9 | CHEMBL324688 | N-[5-METHYL-3-O-TOLYL-ISOXAZOLE-4-CARBOXYLIC ACID AMIDE] BORONIC ACID |
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| Type | Small organic molecule |
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| Emp. Form. | C12H12BClN2O4 |
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| Mol. Mass. | 294.499 |
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| SMILES | Cc1onc(c1C(=O)NCB(O)O)-c1ccccc1Cl |
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| Structure | 
|
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