| Reaction Details |
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 | Report a problem with these data |
| Target | Choline/ethanolamine kinase |
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| Ligand | BDBM50556487 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2056237 (CHEMBL4711238) |
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| Kd | 33000±n/a nM |
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| Citation |  Serrán-Aguilera, L; Mariotto, E; Rubbini, G; Castro Navas, FF; Marco, C; Carrasco-Jiménez, MP; Ballarotto, M; Macchiarulo, A; Hurtado-Guerrero, R; Viola, G; Lopez-Cara, LC Synthesis, biological evaluation, in silico modeling and crystallization of novel small monocationic molecules with potent antiproliferative activity by dual mechanism. Eur J Med Chem207:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Choline/ethanolamine kinase |
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| Name: | Choline/ethanolamine kinase |
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| Synonyms: | CHETK | CHKB | CHKB_HUMAN | CHKL | CK | CKB | CKEKB | Choline kinase beta | Choline kinase-like protein | EK | EKB | Ethanolamine kinase | Ethanolamine kinase beta | choline/ethanolamine kinase beta |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45262.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_108033 |
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| Residue: | 395 |
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| Sequence: | MAAEATAVAGSGAVGGCLAKDGLQQSKCPDTTPKRRRASSLSRDAERRAYQWCREYLGGA
WRRVQPEELRVYPVSGGLSNLLFRCSLPDHLPSVGEEPREVLLRLYGAILQGVDSLVLES
VMFAILAERSLGPQLYGVFPEGRLEQYIPSRPLKTQELREPVLSAAIATKMAQFHGMEMP
FTKEPHWLFGTMERYLKQIQDLPPTGLPEMNLLEMYSLKDEMGNLRKLLESTPSPVVFCH
NDIQEGNILLLSEPENADSLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTHEEWPFYKARP
TDYPTQEQQLHFIRHYLAEAKKGETLSQEEQRKLEEDLLVEVSRYALASHFFWGLWSILQ
ASMSTIEFGYLDYAQSRFQFYFQQKGQLTSVHSSS
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| BDBM50556487 |
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| n/a |
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| Name | BDBM50556487 |
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| Synonyms: | CHEMBL4763249 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H24BrClN2 |
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| Mol. Mass. | 431.796 |
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| SMILES | [Br-].Clc1ccc2c(cc[n+](Cc3ccccc3)c2c1)N1CCCCCC1 |
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| Structure | 
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