| Reaction Details |
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 | Report a problem with these data |
| Target | Phosphoglycerate mutase 1 |
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| Ligand | BDBM50143419 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2058835 (CHEMBL4713836) |
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| IC50 | 2300±n/a nM |
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| Citation |  Jiang, K; Gao, B; Yu, J; Jiang, L; Niu, A; Jia, Y; Meng, T; Zhou, L; Wang, J Design, synthesis, and biological evaluation of 1,3,6,7-tetrahydroxyxanthone derivatives as phosphoglycerate mutase 1 inhibitors. Bioorg Med Chem Lett36:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Phosphoglycerate mutase 1 |
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| Name: | Phosphoglycerate mutase 1 |
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| Synonyms: | BPG-dependent PGAM 1 | PGAM-B | PGAM1 | PGAM1_HUMAN | PGAMA | Phosphoglycerate mutase 1 | Phosphoglycerate mutase isozyme B |
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| Type: | PROTEIN |
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| Mol. Mass.: | 28806.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109479 |
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| Residue: | 254 |
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| Sequence: | MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQ
KRAIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD
VPPPPMEPDHPFYSNISKDRRYADLTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKR
VLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVR
KAMEAVAAQGKAKK
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| BDBM50143419 |
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| n/a |
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| Name | BDBM50143419 |
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| Synonyms: | CHEMBL175336 | Sodium; 3,4-dihydroxy-9,10-dioxo-9,10-dihydro-anthracene-2-sulfonate |
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| Type | Small organic molecule |
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| Emp. Form. | C14H7O7S |
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| Mol. Mass. | 319.267 |
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| SMILES | Oc1c(O)c2C(=O)c3ccccc3C(=O)c2cc1S([O-])(=O)=O |
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| Structure | 
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