| Reaction Details |
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 | Report a problem with these data |
| Target | Acyl-protein thioesterase 1 |
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| Ligand | BDBM50557438 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2059145 (CHEMBL4714146) |
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| IC50 | 9.0±n/a nM |
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| Citation |  Jung, HJ; Nam, EH; Park, JY; Ghosh, P; Kim, IS Identification of BR102910 as a selective fibroblast activation protein (FAP) inhibitor. Bioorg Med Chem Lett37:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Acyl-protein thioesterase 1 |
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| Name: | Acyl-protein thioesterase 1 |
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| Synonyms: | Acyl-protein thioesterase 1/2 | Apt1 | LYPA1_RAT | Lypla1 | Lysosomal phospholipase A1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 24708.49 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_12731 |
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| Residue: | 230 |
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| Sequence: | MCGNNMSAPMPAVVPAARKATAAVIFLHGLGDTGHGWAEAFAGIKSSHIKYICPHAPVMP
VTLNMSMMMPSWFDIIGLSPDSQEDESGIKQAAETVKALIDQEVKNGIPSNRIILGGFSQ
GGALSLYTALTTQQKLAGVTALSCWLPLRASFSQGPINSANRDISVLQCHGDCDPLVPLM
FGSLTVERLKGLVNPANVTFKVYEGMMHSSCQQEMMDVKYFIDKLLPPID
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| BDBM50557438 |
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| n/a |
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| Name | BDBM50557438 |
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| Synonyms: | CHEMBL4789965 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H15F2N5O4S2 |
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| Mol. Mass. | 479.48 |
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| SMILES | FC1(F)C[C@@H](C#N)N(C1)C(=O)CNC(=O)c1csc(CS(=O)(=O)c2ccc(cc2)C#N)n1 |r| |
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| Structure | 
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