| Reaction Details |
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 | Report a problem with these data |
| Target | Steroid hormone receptor ERR1 |
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| Ligand | BDBM50557796 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2060111 (CHEMBL4715112) |
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| EC50 | >10000±n/a nM |
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| Citation |  Shinozuka, T; Ito, S; Kimura, T; Izumi, M; Wakabayashi, K Discovery of a Novel Class of ERR? Agonists. ACS Med Chem Lett12:817-821 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Steroid hormone receptor ERR1 |
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| Name: | Steroid hormone receptor ERR1 |
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| Synonyms: | ERR-alpha | ERR1 | ERR1_HUMAN | ESRL1 | ESRRA | Estrogen receptor-like 1 | Estrogen-Related Receptor, alpha | Estrogen-related receptor alpha | NR3B1 | Nuclear receptor subfamily 3 group B member 1 | Steroid hormone receptor ERR1 | Steroid hormone receptor ERR1 alpha | Steroid hormone receptor ERR1/Estrogen-related receptor alpha (ERRa) | von Hippel-Lindau disease tumor suppressor/Steroid hormone receptor ERR1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45508.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1499891 |
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| Residue: | 423 |
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| Sequence: | MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAG
PGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNE
CEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGP
LAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTI
SWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAA
GLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALL
EYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEA
MMD
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| BDBM50557796 |
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| n/a |
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| Name | BDBM50557796 |
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| Synonyms: | CHEMBL4783029 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20ClNO3 |
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| Mol. Mass. | 333.809 |
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| SMILES | CC(=O)Nc1ccc(Oc2ccc(O)c(c2)C(C)(C)C)c(Cl)c1 |
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| Structure | 
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