| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 2 |
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| Ligand | BDBM50558902 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2067087 (CHEMBL4722340) |
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| IC50 | >10000±n/a nM |
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| Citation |  Pillaiyar, T; Funke, M; Al-Hroub, H; Weyler, S; Ivanova, S; Schlegel, J; Abdelrahman, A; Müller, CE Design, synthesis and biological evaluation of suramin-derived dual antagonists of the proinflammatory G protein-coupled receptors P2Y Eur J Med Chem186:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 2 |
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| Name: | P2Y purinoceptor 2 |
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| Synonyms: | ATP receptor | P2RU1 | P2RY2 | P2RY2_HUMAN | P2U purinoceptor 1 | P2U1 | P2Y purinoceptor 2 | P2Y2 | Purinergic receptor | Purinergic receptor P2Y2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42299.21 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1455361 |
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| Residue: | 377 |
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| Sequence: | MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLC
RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS
ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR
VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK
RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC
LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSR
RTESTPAGSENTKDIRL
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| BDBM50558902 |
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| n/a |
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| Name | BDBM50558902 |
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| Synonyms: | CHEMBL4786491 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H21N3O4 |
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| Mol. Mass. | 403.4305 |
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| SMILES | COC(=O)c1cccc(NC(=O)Nc2cccc(c2)C(=O)Nc2cccc(C)c2)c1 |
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| Structure | 
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