| Reaction Details |
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 | Report a problem with these data |
| Target | Endochitinase A1 |
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| Ligand | BDBM50559065 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2067630 (CHEMBL4722883) |
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| IC50 | 38000±n/a nM |
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| Citation |  Liu, W; Yuan, L; Wang, S Recent Progress in the Discovery of Antifungal Agents Targeting the Cell Wall. J Med Chem63:12429-12459 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Endochitinase A1 |
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| Name: | Endochitinase A1 |
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| Synonyms: | CHIA1_ASPFM | Chitinase (chiA1) | chi1 | chiA1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 83057.83 |
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| Organism: | Neosartorya fumigata (Aspergillus fumigatus) |
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| Description: | Q873Y0 |
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| Residue: | 825 |
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| Sequence: | MVSSKLSFVATAVAALAPLASAFDASSRSNLAIYWGQGPNQLRLSHFCQETSLDIINIGF
INYFPDMSPGHWPGSNFGNQCDGSVYVTNDGVVTKLLSGCHQIMEDIPICQAAGKKVLLS
IGGAYPPDQSILSEDSAVAFATFLWGAFGPVAEGWEGPRPFGDVVVDGFDFDIEHNGGFG
YATMVNTFRQYFNQVPERKFYLSAAPQCIIPDAQLSDAIFNAAFDFIWIQYYNTAACSAK
SFIDTSLGTFNFDAWVTVLKASASKDAKLYVGLPASETAANQGYYLTPDEVESLVSTYMD
RYPDTFGGIMLWEATASENNQIDGAPYADHMKDILLHCDPSPPVTSSSAVPSSTPVTTPS
PSSSAVPSSTPAVSETPSPSSSAVPSSTPVASSTPVVPGTSASSSPVSSSSAIAPSTPVV
PGTSTPSSTPVASSTPVVPGTSASSSPVSSSSAVASSTPVVPGTSVPSSTPAIPGGSSSS
SEAVASSTPLVTLTLTVSPTPAPSSSESSSTDLSSSTQTDVGTAPSQPAGPSTTATATTS
SSSSSTDESSTTVGSGNGNGSGSTTTTAATDSITAAPTATSSATATGATSEPVTITTIIV
TSYIDICPTGFTTVTTTYTTTYCPGTNTATATATVTNPPSGPGGAGSQTTAPTVPEGWTT
TVTVCTQCAAKPTTVTLTLPVTETGSTSTDAVPAPPAATGEGSNPTQPSGASPTGGNGSF
SEEPVPPPAVTQVSTSTEIVTLVRPTSSRPLILGTGTVHPSSTLAVKPSAKPSGQNSGSS
SHVPIPPSYTQEAVSPLSTGAASRVTGLGHGLVLTVLTLSAFFVL
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| BDBM50559065 |
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| n/a |
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| Name | BDBM50559065 |
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| Synonyms: | CHEMBL4746677 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H16N4O |
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| Mol. Mass. | 172.2281 |
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| SMILES | CCCCNC(=N)NC(=O)NC |
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| Structure | 
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