| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor alpha |
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| Ligand | BDBM50121417 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_42430 |
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| Ki | 19000±n/a nM |
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| Citation |  Thor, M; Beierlein, K; Dykes, G; Gustavsson, AL; Heidrich, J; Jendeberg, L; Lindqvist, B; Pegurier, C; Roussel, P; Slater, M; Svensson, S; Sydow-Bäckman, M; Thornström, U; Uppenberg, J Synthesis and pharmacological evaluation of a new class of peroxisome proliferator-activated receptor modulators. Bioorg Med Chem Lett12:3565-7 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor alpha |
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| Name: | Peroxisome proliferator-activated receptor alpha |
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| Synonyms: | NR1C1 | Nuclear receptor subfamily 1 group C member 1 | PPAR | PPAR alpha/gamma | PPAR-alpha | PPARA | PPARA_HUMAN | Peroxisome Proliferator-Activated Receptor alpha | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor alpha (PPAR alpha) |
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| Type: | Enzyme |
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| Mol. Mass.: | 52222.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q07869 |
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| Residue: | 468 |
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| Sequence: | MVDTESPLCPLSPLEAGDLESPLSEEFLQEMGNIQEISQSIGEDSSGSFGFTEYQYLGSC
PGSDGSVITDTLSPASSPSSVTYPVVPGSVDESPSGALNIECRICGDKASGYHYGVHACE
GCKGFFRRTIRLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSE
KAKLKAEILTCEHDIEDSETADLKSLAKRIYEAYLKNFNMNKVKARVILSGKASNNPPFV
IHDMETLCMAEKTLVAKLVANGIQNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANL
DLNDQVTLLKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFD
FAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDI
FLFPKLLQKMADLRQLVTEHAQLVQIIKKTESDAALHPLLQEIYRDMY
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| BDBM50121417 |
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| n/a |
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| Name | BDBM50121417 |
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| Synonyms: | CHEMBL119646 | Lithium; 2-(2,4-dichloro-benzoylamino)-5-(2-methylsulfanyl-ethoxy)-benzoate |
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| Type | Small organic molecule |
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| Emp. Form. | C17H14Cl2NO4S |
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| Mol. Mass. | 399.269 |
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| SMILES | CSCCOc1ccc(NC(=O)c2ccc(Cl)cc2Cl)c(c1)C([O-])=O |
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| Structure | 
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