| Reaction Details |
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 | Report a problem with these data |
| Target | Stromelysin-1 |
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| Ligand | BDBM26193 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_205633 (CHEMBL813241) |
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| Kd | >25000000±n/a nM |
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| Citation |  Hajduk, PJ; Shuker, SB; Nettesheim, DG; Craig, R; Augeri, DJ; Betebenner, D; Albert, DH; Guo, Y; Meadows, RP; Xu, L; Michaelides, M; Davidsen, SK; Fesik, SW NMR-based modification of matrix metalloproteinase inhibitors with improved bioavailability. J Med Chem45:5628-39 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Stromelysin-1 |
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| Name: | Stromelysin-1 |
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| Synonyms: | MMP-3 | MMP3 | MMP3_HUMAN | Matrix metalloproteinase (2 and 3) | Matrix metalloproteinase 3 | Matrix metalloproteinase-3 | Matrix metalloproteinase-3 (MMP-3) | Matrix metalloproteinase-3 (MMP3) | SL-1 | STMY1 | Stromelysin 1 | Transin-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 53973.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08254 |
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| Residue: | 477 |
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| Sequence: | MKSLPILLLLCVAVCSAYPLDGAARGEDTSMNLVQKYLENYYDLKKDVKQFVRRKDSGPV
VKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGHFRTFPGIPKWRKTHLTYRIVN
YTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNV
LAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLY
HSLTDLTRFRLSQDDINGIQSLYGPPPDSPETPLVPTEPVPPEPGTPANCDPALSFDAVS
TLRGEILIFKDRHFWRKSLRKLEPELHLISSFWPSLPSGVDAAYEVTSKDLVFIFKGNQF
WAIRGNEVRAGYPRGIHTLGFPPTVRKIDAAISDKEKNKTYFFVEDKYWRFDEKRNSMEP
GFPKQIAEDFPGIDSKIDAVFEEFGFFYFFTGSSQLEFDPNAKKVTHTLKSNSWLNC
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| BDBM26193 |
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| n/a |
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| Name | BDBM26193 |
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| Synonyms: | 2-Hydroxybenzoate, I | 2-hydroxybenzoic acid | CHEMBL424 | phenol derivative, 7 | salicylic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C7H6O3 |
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| Mol. Mass. | 138.1207 |
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| SMILES | OC(=O)c1ccccc1O |
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| Structure | 
|
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