| Reaction Details |
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 | Report a problem with these data |
| Target | Retinoic acid receptor RXR-beta |
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| Ligand | BDBM50122349 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_197069 (CHEMBL806658) |
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| Kd | 15±n/a nM |
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| Citation |  Farmer, LJ; Zhi, L; Jeong, S; Lamph, WW; Osburn, DL; Croston, G; Flatten, KS; Heyman, RA; Nadzan, AM Retinoic acid receptor ligands based on the 6-cyclopropyl-2,4-hexadienoic acid. Bioorg Med Chem Lett13:261-4 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinoic acid receptor RXR-beta |
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| Name: | Retinoic acid receptor RXR-beta |
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| Synonyms: | Nr2b2 | RXRB_MOUSE | Retinoid X receptor beta | Rxrb |
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| Type: | PROTEIN |
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| Mol. Mass.: | 55877.78 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_196588 |
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| Residue: | 520 |
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| Sequence: | MSWATRPPFLPPRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAGEQQALEP
EPGEAGRDGMGDSGRDSRSPDSSSPNPLSQGIRPSSPPGPPLTPSAPPPPMPPPPLGSPF
PVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGLHCPP
PPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQ
RNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGDGAGGAPEEMPVDRILEAELAVEQ
KSDQGVEGPGATGGGGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLR
AGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMRM
DKTELGCLRAIILFNPDAKGLSNPGEVEILREKVYASLETYCKQKYPEQQGRFAKLLLRL
PALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
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| BDBM50122349 |
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| n/a |
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| Name | BDBM50122349 |
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| Synonyms: | (2E,4E)-6-[1-(6-tert-Butyl-1,1-dimethyl-indan-4-yl)-cyclopropyl]-3-methyl-hexa-2,4-dienoic acid | CHEMBL88216 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H34O2 |
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| Mol. Mass. | 366.5363 |
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| SMILES | C\C(\C=C\CC1(CC1)c1cc(cc2c1CCC2(C)C)C(C)(C)C)=C/C(O)=O |
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| Structure | 
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