| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 5 |
|---|
| Ligand | BDBM50123737 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_144136 (CHEMBL750714) |
|---|
| Ki | 1.7±n/a nM |
|---|
| Citation |  Elliott, RL; Oliver, RM; Hammond, M; Patterson, TA; She, L; Hargrove, DM; Martin, KA; Maurer, TS; Kalvass, JC; Morgan, BP; DaSilva-Jardine, PA; Stevenson, RW; Mack, CM; Cassella, JV In vitro and in vivo characterization of 3-[2-[6-(2-tert-butoxyethoxy)pyridin-3-yl]-1H-imidazol-4-yl]benzonitrile hydrochloride salt, a potent and selective NPY5 receptor antagonist. J Med Chem46:670-3 (2003) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Neuropeptide Y receptor type 5 |
|---|
| Name: | Neuropeptide Y receptor type 5 |
|---|
| Synonyms: | NPY-Y5 | NPY5R_RAT | Neuropeptide Y receptor type 5 | Npy5r | Npyr5 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 50435.58 |
|---|
| Organism: | Rat 6B |
|---|
| Description: | NPY-Y5 NPY5R Rat 6B::Q63634 |
|---|
| Residue: | 445 |
|---|
| Sequence: | MEFKLEEHFNKTFVTENNTAAARNAAFPAWEDYRGSVDDLQYFLIGLYTFVSLLGFMGNL
LILMAVMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKAMCHIMPFL
QCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSL
VELKETFGSALLSSKYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISC
GLSHKENRLEENEMINLTLQPSKKSRNQAKTPSTQKWSYSFIRKHRRRYSKKTACVLPAP
AGPSQGKHLAVPENPASVRSQLSPSSKVIPGVPICFEVKPEESSDAHEMRVKRSITRIKK
RSRSVFYRLTILILVFAVSWMPLHVFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLN
PILYGFLNNGIKADLRALIHCLHMS
|
|
|
|---|
| BDBM50123737 |
|---|
| n/a |
|---|
| Name | BDBM50123737 |
|---|
| Synonyms: | 3-{2-[6-(2-tert-Butoxy-ethoxy)-pyridin-3-yl]-3H-imidazol-4-yl}-benzonitrile | CHEMBL161724 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H22N4O2 |
|---|
| Mol. Mass. | 362.425 |
|---|
| SMILES | CC(C)(C)OCCOc1ccc(cn1)-c1nc(c[nH]1)-c1cccc(c1)C#N |
|---|
| Structure | 
|
|---|
Search and Browse
